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Bacteremia with the Triad Osteomyelitis, Deep Vein Thrombosis, and Pulmonary Septic Emboli in Pediatric Age: A Case Report

Published on: 25th October, 2025

Acute osteomyelitis (AOM) is defined as an inflammation of the bone secondary to infection. Among the most common complications of AOM is the development of a periosteal abscess and the extension of the focus locally to muscle (pyomyositis) and/or joint (osteoarthritis). However, complications with much lower incidence have been described, including deep vein thrombosis (DVT) and septic pulmonary embolisms (SPE), mainly associated with S. aureus infections. The AOM + DVT + ESP triad is a fairly uncommon entity in the pediatric population; however, if it is not diagnosed and treated in time, it implies a high morbidity and mortality. Treatment, which must be early and aggressive, includes targeted antibiotic therapy, anticoagulation, and focused control surgery. In this article, we describe the case of a 14-year-old boy with disseminated staphylococcal infection associated with the triad AOM+ DVT + SPE.
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