Background: Biotechnology is a multidisciplinary field based on the expertise of molecular biology, chemistry, biochemistry, chemical and biological engineering, and digital computing. Biotechnology plays an important role in modern forensic science, driving advances in analytical tools and techniques.This review study provides a brief overview of applications, highlighting advances in forensic biotechnology and key technologies involved in the domains of genomics and DNA analysis, microbial forensics, forensic medicine, and forensic serology. The integration of forensic expertise with technology has increased the accuracy, sensitivity, and efficiency of forensic casework.Conclusions: This interdisciplinary field extends beyond its usual association with biology to also include chemistry, fingerprint analysis, and toxicology, among others. Continued progress and innovation in this advanced field will further enhance investigative capabilities and facilitate the pursuit of justice.
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