Articles

Techno-econophysics’ Fractal Involving of Exergy Remarks

Published on: 4th September, 2024

Inclusively new to econophysics studies, herewith proposed technoeconophysics as part of techno-economy, econophysics & sociophysics to interpret the description between probability and hypothesis found between fractal realms and econophysics of markets, physics markets, or stock markets any chaotic evidence [exergy destructive] could present if effective & efficient criterion doesn’t comply. A more precise iterative study ought to be held to configure how fractal dimension is involved in the techno-econophysics study of the Helium Nat Gas Project which is not integer, but also proofed numerically & analytically.
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Evaluation of the Social Return on Investment (SROI) in Patients with Hepatitis C. The Case of the Mobile Outreach Program (MOP)

Published on: 9th September, 2024

The World Drug Report highlights that the prevalence of hepatitis C virus (HCV) is one of the leading causes of cirrhosis and hepatocellular carcinoma globally. This report estimates that HCV is responsible for the annual death of around 700,000 people due to liver disease and is associated with high levels of morbidity and mortality with high health and socio-economic costs. This exploratory study aims to evaluate the socio-economic return provided by HCV treatment of individuals integrated into the MOP developed by the NGO Ares do Pinhal in Portugal. Using the SROI (Social Return on Investment) methodology is estimated that for every euro invested in this program, the return for society is 3,75€. This is a significantly positive SROI value, highlighting the importance of this investment in the creation of monetized value for society, as well as to provide greater well-being to those who need it and to society as a whole.
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Comparative Analysis of Water Wells and Tap Water: Case Study from Lebanon, Baalbeck Region

Published on: 5th September, 2024

Water deficit is a fundamental factor in public health and economic growth. Water supply and population growth are directly linked to water demand. The physio-chemistry and microbiology analysis of water is utmost significance in dietary requirements. Drinking water has the main concern especially it affects food security. This study includes a number of representative sites where 24 water samples (from wells, reservoirs and tap water) were analysed. These sites are located in the western villages of Baalbeck, the main city of the Bekaa Plain in Lebanon where the analysed water is used mainly for domestic needs and for irrigation. This study  investigates the physiochemical and microbiological properties. Among the selected sites, Hawsh Barada site shows a strong contamination by nitrate. At the Nabi Rashaded (tap), Beit Shema and Bednayel (borehole and tap), contamination above the norm by zinc ion was noted. From a microbiological point of view, Hawsh barada, Nabi-Rashadeh, Hawsh-bay, and Beit shema are markedly polluted and do not meet the standard for drinking water. Hence, water quality in Hawsh barada, Nabi-Rashadeh, Hawsh-bay, Beit shema and Bednayel are not suitable for drinking, and this must be informed to decision makers who can act implementing environmental controls for health protection in the studied region.
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Mesofractal Modeling of Biosystems & Organic Spintronics

Published on: 4th September, 2024

Mesoscopic modeling of complex systems involves thermodynamic nonequilibrium of discrete scaling. Further from quantum correlation on a chip retrieved quantum nonlinear optics with single photons enabled by strongly interacting atoms. Accompanied by mesofractals as the development of meso & micro size fractal structures is required to mimic various biological systems for various functions. Showed through fluorapatite in gelatin‐based nanocomposite, fractal in DNA knots driven by balance of fission & fusion in mtDNA/mitochondrial DNA mechanism, for optical engines for light energy detection described the proportional integral derivative [PI(D)]‐controller set in microbial cells to HCCI/Homogeneous Charge Compression Ignition.
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COVID-19, Long COVID, and Gastrointestinal Neoplasms: Exploring the Impact of Gut Microbiota and Oncogenic Interactions

Published on: 4th September, 2024

Background: The impact of COVID-19 and long-term COVID-19 on gastrointestinal neoplasms remains underexplored. The current review investigates the potential link between these conditions and the role of gut microbiota in mediating oncogenic processes. Dysbiosis, characterized by alterations in gut microbial composition, may exacerbate inflammation and immune dysregulation, contributing to cancer development.Methods: A comprehensive literature review was conducted using databases including PubMed, Scopus, Embase, SciELO, and Web of Science. Inclusion criteria encompassed studies published between 2020 and 2024 that explored the intersection of COVID-19, long-term COVID-19, and gastrointestinal cancers. The articles were critically appraised for quality and relevance, and data were synthesized to elucidate common mechanisms and outcomes.Results: The review identifies several mechanisms by which gut microbiota may influence cancer risk in COVID-19 patients. Persistent inflammation, oxidative stress, and immune dysfunction observed in Long COVID were associated with dysbiosis. Specific microbial metabolites, such as secondary bile and short-chain fatty acids, were implicated in promoting tumorigenesis. Comparative analysis of studies suggests that SARS-CoV-2-induced dysbiosis may heighten susceptibility to gastrointestinal cancers, particularly in patients with prolonged post-infection symptoms.Conclusion: The findings underscore the need for further research to clarify the role of gut microbiota in cancer development among COVID-19 patients. These mechanisms could inform preventative strategies and therapeutic interventions, particularly for those experiencing COVID. The review highlights gaps in current knowledge and advocates for longitudinal studies to assess the long-term effects of COVID-19 on gastrointestinal health.
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Nanoencapsulated Extracts from Leaves of Bauhinia forficata Link: In vitro Antioxidant, Toxicogenetic, and Hypoglycemic Activity Effects in Streptozotocin-induced Diabetic Mice

Published on: 5th September, 2024

In this study, we evaluated the assessed the hypoglycemiant, toxicogenetic and genotoxic effects of nanoencapsulate extracts of Bauhinia forficata Link. Phytochemical evaluations of extracts were carried out, as well as the evaluation using HPLC-MS and of antioxidant capacity in vitro. DM2 was induced in mice with streptozotocin and extracts were given orally for 28 days. That dried extract from infusion (ESIN) had a higher rate of bioactive compounds compared to the dried extract from decoction (ESDC), and higher antioxidant capacity. Glucose levels decreased from 77.26% to 57.79% and 45.15% after supplementation with ESIN (200 and 600 mg/kg/day) and ESDC (600 mg/kg/day), respectively, when compared to the diabetic group treated with metformin (600 mg/kg/day) (21.53%), with an improvement in the glycemic response e recovery of pancreatic β cells. Thus, our study has shown that these extracts exhibit hypoglycemiant activity, with a beneficial effect superior to metformin, as a result they could be considered as potential therapeutic agents for application in pharmaceutical formulations in the treatment of DM2.
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Oral Suspension as Versatile Galenic Formulation in Pediatry

Published on: 3rd September, 2024

In the last years, there has been an increase in the prescription of drugs in pediatry as a pharmaceutical form of oral suspension. The same is true in commerce there are various producers that provide specific ready-for-use excipients to make more easier to prepare OS in the galenic laboratory. The aim of this work is to verify the advantages of this pharmaceutical form to cover pediatric dosages vs. other forms and also to overcome shortcomings of some crucial registered drugs. In this work scientific literature is reported that also relates to some ready-for-use products as bases-vehicle for suspension and some formulations of interest.
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Poor Diet Leading to the Increasing Risk of Atherosclerosis in the World

Published on: 3rd September, 2024

Atherosclerosis Ischemic Cardiovascular Disease (ASICD), one of the leading causes of global deaths, is mainly caused due to the development of plaque on the inner walls of arteries of the human heart. Ischemia refers to the lack of enough oxygen (O2), nutrient delivery, and improper waste removal in the cardiac cells. About 90% of cardiovascular diseases in the present world are due to the formation of lipid/cholesterol-based plaques that can form under the lining of the smooth epithelial blood cells. In the US, a study published in the Journal of the American College of Cardiology estimated that poor diet is responsible for about 45% of Cardiovascular Disease. Atherosclerosis doesn’t cause much effect until and unless the plaque becomes unstable due to the accumulation of thrombus that shows Acute Coronary Syndrome. Acute Coronary Syndrome is the result of blockage of blood vessels leading to Myocardial Infarction (Unstable Angina Pectoris). Cardiac Cells require a sufficient amount of Oxygen to function properly. Thus, the demand and supply of oxygen to the cardiac cells should be properly balanced. Atherosclerosis Ischemic Cardiovascular syndrome can worsen if the person is more involved in exercise or emotional stress because at that time their body requires higher oxygen but blood flow gets disrupted due to the formation of plague. Later in the paper, we will discuss the New York Heart Association classification, followed by the top 3 poor diets that are considered to be increasing the cases of cardiovascular disease around the world.
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Additional Gold Recovery from Tailing Waste By Ion Exchange Resins

Published on: 30th August, 2024

The article describes the gamma activation analysis method used to determine the gold content in rock samples using the Aura measuring complex. The physicochemical basis of gold extraction in the process of cyanide leaching is considered. The technology for extracting gold from solutions of tailing waste “ponds” of tailings dumps of hydrometallurgical plants of the Joint Stock Company “Navoi Mining and Metallurgical Combine” (JSC NMMC) is presented. It has been shown that in the dynamic mode of sorption of tailing waste solutions acidified to pH = 3.3÷3.5 through AM-2B and VP-1P ion exchange resins, gold is sorbed on the AM-2B anion exchanger up to 3.9 mg/g and on the VP-1P anion exchanger up to 1.5 mg/g. It has been shown that when solutions of tailing waste are exposed to ammonia, ammonia complex compounds of base metal impurities are formed, which decompose, while the gold cyanide complex does not decompose and is sorbed on the AM-2B ion exchange resin up to 3.0 mg/g. The mechanisms of the chemical reactions of the process of extracting gold from tailing waste and the technological scheme of the installation for extracting gold from solutions of the tailing waste “pond” are presented.
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Quantifying Levels of Selected Metals in Different Rice Brands

Published on: 29th August, 2024

This research focused on assessing the levels of selected metal contamination in seven different rice brands (Jasmine, Basmati, Mapembe, Morogoro, Shinyanga, Mbeya, and Cheju). Cheju rice was obtained from local producers from the Cheju area in Zanzibar, while the remaining rice brands namely, Jasmine, Basmati, Mapembe, Morogoro, Shinyanga, and Mbeya were randomly taken from local markets at Darajani and Mwanakwerekwe in Zanzibar. Samples were prepared in accordance with applicable Safe Operating Procedures (SOPs) and laboratory SOPs using information provided by field sample preparation. The samples were ground to fineness and an aliquot of about 10.0 g was measured on the beam balance and mounted on the sample holders for laboratory analysis. An Energy Dispersive X-Ray Fluorescence (EDXRF) technique with a Rigaku NEX CG EDXRF model spectrometer was used for metal analysis. The study revealed that the percentage of metal contamination varied considerably from one rice brand to another, with Basmati and Jasmine rice each exhibiting a contamination level of 50%, while Shinyanga, Mbeya, Mapembe, and Cheju rice showed a level of 25% each. Notably, Morogoro rice had no observable heavy metal contamination. Additionally, a significant positive correlation was observed between several metal pairs: Au and Cr (r² = 1.00), Au and Ti (r² = 0.613), Cr and Ti (r² = 0.613), Ni and Pb (r² = 0.748), Ni and Hf (r² = 0.660), Pb and Hf (r² = 0.656), and Ti and Sn (r² = 0.671). The individual occurrence (percentage) for metals across all rice brands were as follows: 71.42% for Sn, and 28.57% for Hf, Ni, Pb, and Ti, while traces of Au, Cr, and Y each had an occurrence level of 14.28%. While Morogoro rice showed no metal discernible analyzed heavy metal contamination, the other rice brands were observed to have a considerable heavy metal contamination trend. The patterns of metal occurrence in each rice brand were observed as follows: Basmati: Sn > Ti > Au > Cr; Jasmine: Sn > Hf > Ni > Pb; Shinyanga: Sn > Pb; Mbeya: Sn > Hf; Mapembe: Sn > Ti; Cheju: Ni > Y. The patterns, then yield the ranking of metal contamination across all seven rice brands from lowest to highest is as follows: Morogoro < (Mapembe, Cheju, Mbeya, Shinyanga) < (Jasmine, Basmati). Furthermore, the data analysis indicated that the concentrations of Cr (1.08 mg/Kg), Ni (4.65 mg/Kg), and Pb (3.05 mg/Kg) detected in the samples surpassed the maximum permissible limits established by WHO/FAO which were 1.0 mg/Kg, 0.10 mg/Kg and 0.20 mg/Kg respectively. Consequently, the study concludes that Morogoro rice is the most superior and considered the safest choice for consumption, while Jasmine and Basmati rice are associated with higher levels of metal contamination. Thus, it is highly recommended that Tanzania intensify its rice cultivation efforts to reduce reliance on rice imports from other nations.
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