“Thyroid”: Letter to the Editor, Radioactive Iodine: A Living History
Published on: 7th March, 2024
The history of the origin of the medical uses of Radioiodine (RAI) has been compromised by false narratives as recently as June 2023 in the “Thyroid “article “Radioactive Iodine: A Living History”. Primary sources document Dr. Saul Hertz (1905 - 1950) as solely conceiving of the medical uses of RAI, being the first and foremost to develop the experimental data, bringing RAI from bench to bedside, and extending the use of radionuclides to diagnose and/or treat cancer and other conditions. Dr Hertz predicted and worked toward conquering cancer with other radionuclides. Saul Hertz overcame the racism of his time, a world war interrupting his first clinical study, a strong pushback from the surgeons, and unethical medical publishing practices. Today, Nuclear Medicine, Radiopharmacy, Medical Physics, and other specialties are collaborating and actively building on Saul Hertz’s enduring foundational work.
Caring Difficulties of Parents’ Towards Children with Cerebral Palsy
Published on: 16th May, 2017
OCLC Number/Unique Identifier: 7317593954
Children with cerebral palsy may have one or more of mental, psychomotor, visual, audio or speech problems. Not being a well-defined disease with clear boundaries, it is regarded as a set of conditions caused by various reasons. In this regard, children with CP have to depend on their families or caregivers and cope with physical, mental, social and economic problems due to their condition. Therefore, it turns out to be crucial to determine the needs of the family with children with CP so that the programs that will assist them during this process can be developed. The study further revealed that the parents of the children with cerebral palsy needed information about controlling their children’s behaviors and teaching them certain behaviors; they needed to talk to the teacher and/or therapist of the child; they needed support about making time for themselves; they needed community services about finding a care center or a nursery suitable for their children’s needs.
Rapid Upper Limb Assessment (RULA) and Rodgers Muscle Fatigue Analysis (RMFA) of Dentists using Optical Microscope, Loupes, or No Magnification during Endodontic Access: A Pilot Study
Published on: 29th August, 2024
Dentistry is a challenging and demanding physical profession, and this impacts not only the quality of the task outcomes but also the professional’s quality of life. The nature of dentistry demands prolonged static and awkward seated postures, frequent motions, positioning struggles, and working distances to the oral cavity for strategic procedure management, which become cumulative challenges over the working days, prone to discomfort, pain, or injuries, and musculoskeletal disorders for the operator.The limitations of the naked eye in dentistry, particularly in terms of visual information and resolution, underscore the need for visual aids. These aids are crucial for achieving the precision required for accurate procedures. Also, visual aids, such as magnifying loupes and the operative microscope, have been in the market for a while, and their proper use has shown ergonomic benefits that promote a neutral working posture and changes in work practice-oriented to control unbalanced awkward posture and motions.In this study, the Rapid Upper Limb Assessment RULA compares the posture between naked-eye dentistry, conventional loupes, and operative microscope, and with the observational assessment, determine the risk of developing musculoskeletal disorders and the need for priority of change. The Rodgers muscle fatigue analysis RMFA is used to predict fatigue in the muscular regions of the body during specific dental tasks.
The value of routine ultrasound at discharge to identify patients at risk of developing symptomatic lymphoceles after kidney transplantation: A case-cohort study
Published on: 9th July, 2019
OCLC Number/Unique Identifier: 8199192017
Introduction: Ultrasound examination is frequently used to evaluate the graft after renal transplantation and to detect possible lymphoceles. The first ultrasound scan in our hospital is normally performed on the day of discharge. We questioned whether perirenal fluid collections detected by ultrasound examination at discharge are predictive for future symptomatic lymphoceles.
Methods: All ultrasound reports of all renal transplant recipients treated in our hospital between January 2010 and December 2017 were collected and screened for abnormalities such as fluid collections. Patients that developed a symptomatic lymphocele were compared with a control group from the same cohort. Sensitivity and specificity of ultrasound examination to detect symptomatic lymphoceles were calculated for the primary and consecutive ultrasounds tests.
Results: There were no significant differences at baseline characteristics between the Symptomatic lymphocele group and control group, with the exception of mean age at kidney transplantation (47 ± 17 years in the control group vs. 56 ± 13 years in the symptomatic lymphocele group, p=0.02).
The ultrasound examination at discharge had a sensitivity of 31% and specificity of 87% to detect future symptomatic lymphoceles. The positive predictive value was only 10%. The second ultrasound test had the best test variables to detect symptomatic lymphoceles with a sensitivity of 93% and a specificity of 87% and a predictive value of 28%.
Conclusion: Routinely use of ultrasound testing on the day of discharge does detect perirenal fluid collections, but is not predictive for development of symptomatic lymphoceles in the future.
Virulence Genes in Pseudomonas Aeruginosa Strains Isolated at Suez Canal University Hospitals with Respect to the Site of Infection and Antimicrobial Resistance
Published on: 5th July, 2019
OCLC Number/Unique Identifier: 8197683883
Background: Pseudomonas aeruginosa is one of the top five pathogens causing healthcare-associated infections. Biofilm formation is nowadays a major problem. Aim: The aim of this study was to examine the prevalence of virulence genes in clinical isolates of Pseudomonas aeruginosa at Suez Canal University Hospitals with respect to the site of infection and microbial resistance of the strains.
Materials and methods: A cross-sectional descriptive study was carried out on 47 Pseudomonas aeruginosa strains collected from hospitalized patients from December 2015 to August 2017. To detect biofilm formation, we used Tissue Culture Plate Method. The virulence genes (toxA, algD, nan1, pslA and pelA) were amplified using PCR technique.
Results: The highest sensitivity was to Imipenem and Ciprofloxacin (85.1% and 68.1% respectively).With respect to the virulence genes, toxA gene was detected in 45 isolates (95.7%), algD gene in 42 isolates (89.4%), pslA in 42 isolates (89.4%) %), pelA cted in 41 isolates (87.2%) and nan1gene was detected in 19 isolates (40.45%).
Conclusions and Recommendations: We conclude that there is relationship between virulence genes and biofilm formation in Pseudomonas aeruginosa. We recommend the expansion of work on a larger sample size in a longer period of time.
Knowledge, perception and practices of Suez Canal University students regarding Hepatitis C Virus infection risk and means of prevention
Published on: 5th July, 2019
OCLC Number/Unique Identifier: 8197638609
Background: Egypt has the highest prevalence of HCV in the world as more than 10% of population suffers from HCV infection. High prevalence of HCV in Egypt represents a great risk to the whole population that requires aggressive mass awareness regarding routes of infection and means of prevention.
Aim: To determine the knowledge and practices of university students in 5 different faculties in Suez Canal University regarding HCV infection and means of prevention.
Materials and method: A cross sectional study was conducted in five university faculties in Suez Canal University.
Results: The study included 698 students from the faculties of Medicine, Pharmacy, Dentistry, Nursing and Education in Suez Canal University in Ismailia city in Egypt. There was a statistically significant difference regarding the knowledge about the diagnosis, complications and routes of transmission total knowledge score for HCV among the different faculties.
Conclusion and Recommendations: Knowledge and practices of university students in Suez Canal University is partial to weak especially in students of non-biological sciences who have less close contact with patients
Phytochemical and pharmacological properties of Jatropha dioica
Published on: 10th February, 2023
Jatropha dioica sesse ex cerv is a specie native to Mexico and Texas, commonly known as “sangre de drago“, its name is due to its colorless juice turning dark at exposure to the wind. This mini-review aims to collect information about the phytochemical and pharmacological properties of Jatropha dioica. The phytochemicals identified are diterpenes, (citlalitrione, jatrophone and riolozatrione), β-sitosterol, oxalic acid and ellagic acid. The stems, whole plant, or the root of J. dioica in traditional medicine are used to avoid hair loss, as an antibacterial, and antiviral, to strengthen teeth, and to heal some injuries among others uses. Among the biological activities attributed to Jatropha dioica are found in antiviral activity, antifungal, antimicrobial, chemopreventive, anti-hyperglycemic and cytotoxic. However, the little information about the chemical composition of this species and the scarce scientific studies validating its pharmacological properties make J. dioica an interesting species to study.
Handwashing in healthcare today: Why haven’t we gotten better?
Published on: 25th April, 2019
OCLC Number/Unique Identifier: 8163900187
In 2010, a study identified that only about 40% of doctors and other health care providers comply with proper hand hygiene techniques in hospitals and other healthcare facilities. These statistics are alarming as healthcare professionals are the ones who set the gold standard for hygiene and sterility, but they continue to find it difficult to demonstrate this standard in every practice [1]. Even with The Joint Commission supporting that hand hygiene as the most critical intervention for preventing healthcare-associated infections (HCAIs), the compliance rate for hand hygiene has not drastically improved [2]. The goal of this article brief is to answer the question why hasn’t handwashing improved even with the evidence to support that proper hand hygiene decreases HCAIs?
Comparison of Trigger Point Lidocaine Injection and Stabilization Splint Use in Myofascial Orofacial Pain Treatment
Published on: 20th September, 2024
Objective: This study aims to compare the short-, medium-, and long-term efficacy of trigger point local anesthetic injection and stabilization splint use for myofascial orofacial pain.Materials and methods: Group 1 comprised 15 patients who received trigger point local anesthetic injections (LAI), while Group 2 comprised 15 patients who were treated with a stabilization splint (SS). Analysis of pain-free maximum mouth opening (MMO) measurements, jaw disability checklists (JDC), short-form McGill pain questionnaires (SF-MPQ), and Visual analog scales (VAS) were used for comparison between the groups.Results: The LAI group showed a significantly greater increase in pain-free MMO in all terms (p < 0.001) and had significantly lower values on the JDC in both the medium (p = 0.026) and the long term (p = 0.006). The SF-MPQ was significantly lower in the medium term (p = 0.001) in the LAI group; the VAS showed a significantly greater decrease in the short (p = 0.016) and medium terms (p < 0.001) in the LAI group.Conclusion: The results indicate that a treatment choice can be made between TN lidocaine injection and occlusal splint based on patient tolerance.
Acute Gas Toxicity at Work: A Tale of Two Cases with Review of Literature
Published on: 4th July, 2025
Hydrogen sulphide [H2S] is created when sewage material breaks down. The well-known "rotten egg" odour is linked to H2S at low quantities. It is a colourless and odourless gas that, at greater quantities, can cause cerebral and respiratory depression, fast unconsciousness, and impending death. As a sad occupational accident, worker deaths in septic tanks or sewage systems are not unusual in medico-legal practice.Death is attributed to poisoning with hazardous gases, particularly hydrogen sulphide, but the depletion of oxygen in the air due to an excess of carbon dioxide is not mentioned. Colleague fatalities are frequently linked to deaths in similar situations. Two tragic accidents that resulted in victim deaths are detailed in this paper. Here, the morphological findings—pulmonary diseases, submucosal/sub-serosal congested haemorrhage, and discolouration from postmortem staining—were discovered in both cases. A detailed scene investigation about the potential for life-threatening H2S poisoning for the assistants, the characteristic rotten egg smell that may be detected on the corpses, and the previously described morphological results should be the foundation for any suspicion of a deadly H2S poisoning. A qualitative and, if feasible, quantitative study of H2S should be performed to confirm the diagnosis.
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