The Ailments and their Treatments & Function of Integumentary Systems: A Details Review
Published on: 7th January, 2025
A details development in recent dermal studies being carried out and purposed dermal studies is investigated in this research review globally and the various disease and process functions and treatment with symptoms and etiology and pathophysiology of skin-related issues are studies and practically feasible solution of various integumentary systems related problem and it’s function is researched and almost 30 types of common skin related diseases and remedies studies by researcher and it’s company KIRDPL in global perspectives and especially in tropical climate zone in various cases in patients is mentioned including plastic surgery to gene therapy and dermabrasion to the genetic disease as well. The integumentary systems in the animal kingdom as a whole are focused and homosapiens' human dermal functions and their development and future developments of stem cells laboratory-grown skin coats of different colors for shedding and treatments of cancerous skin and integumentary system and gene therapy of the ailments are discussed.
Severe Infantile Transaldolase deficiency: A case report
Published on: 24th July, 2019
OCLC Number/Unique Identifier: 8207287340
Transaldolase TALDO deficiency is a rare autosomal recessive disorder of the pentose phosphate pathway. It has variable presentations with poor outcome when present early in life. We present a young Saudi infant with a fatal early presentation of TALD deficiency.
The Immunitary role in chronic prostatitis and growth factors as promoter of BPH
Published on: 25th April, 2018
OCLC Number/Unique Identifier: 7666286870
In the actual medical therapy of BPH, we can see: antibiotics, alpha blockers, 5-ARI, fitotherapeutics/natural products (Serenoa repens) with different which display clinical activities and other molecules such as FANS (local or systemic dosage forms) cortisones and others. Relationship between immune systems and chronic prostatitis are strictly involved in BPH progression. A vicious cycle that involve chronic flogosis, tissue remodeling, grow factors, inhibition of apoptosis, and other phenomena. Observing BPH pathogenesis under an immunologic point of view make possible to search new pharmacological strategies, to improve actual therapy.
The aim of this work is to observe some relevant literature in our opinion related the management of BHP and its progression under a pharmaceutical and immunological point of view. A deep knowledge in the pharmaceutical properties of some molecules (antimicrobials, anti-phlogosis agents, Anti-androgenic agents, alpha blockers, 5-ARI and other treatments, techniques, interventions or instruments) can help the physicians to pick the right choice.
Drawings as learning aid for the human anatomy students’ based evaluation
Published on: 5th October, 2017
OCLC Number/Unique Identifier: 7286428771
Introduction: One of the essential requirements for efficient oral and maxillofacial surgeon is comprehensive knowledge in anatomy of head and neck regions. Authors believe that asking students to draw anatomical sketches will assist them to improve their imaginary memory for human anatomy. However, drawing, as learning aid in anatomy, has not been given enough attention as a learning aid for human anatomy.
Aim of the study: To determine dental students’ level of appreciation to drawings as practical learning aid in human anatomy.
Materials and methods: Seventy nine first year dental students in Ibn Sina University for Medical and Pharmaceutical Sciences College of Dentistry for the academic year 2016-2017, were requested to complete a questionnaire. The questions were mostly related to the importance of drawing in anatomy and its relation to Anatomy education. The participation in the questionnaire was optional.
Results: This study showed highly significant relationship between the ability to understand anatomy subject and the importance of drawing (P=0.006). It also showed highly significant relationship between the importance of drawings and giving clinical examples during lectures or anatomical labs (P=0.006). Furthermore, the results showed no significant relationship between the importance of drawings and the load of anatomical material, introduced in anatomical lectures and labs (P=0.639).
Conclusion: Anatomical drawings, from first year dental students’ perspective, are a useful learning tool and can relate to different aspects of proper education of human anatomy. Drawings can be implemented as practical tool in human anatomy curriculum for undergraduate dental education.
Alternative treatment methods in eyes with pseudophakic cystoid macular edema
Published on: 3rd January, 2019
OCLC Number/Unique Identifier: 7970379228
Cystoid macular edema is a common cause for unexplained painless vision loss after cataract surgery. Even the pathogenesis of pseudophakic cystoid macular edema (PCME) still remains undefined, it can most frequently occur in eyes with high vasoactive profile, had complicated cataract surgery such as posterior capsule rupture and risk of inflammation. Increased inflammation, ultimately leading to the breakdown of the blood-retinal barrier and cystic accumulation of extracellular intraretinal fluid. The natural history of PCME is spontaneous resolution without any treatment in most of patient, but it may take weeks or months, in addition permanent visual morbidity may occur in some cases. Therefore there is lack of consensus regarding treatment approach for this common ocular condition.
In this review treatment alternatives of PCME and its relation with underlying patho-physiologic mechanism are evaluated.
Benign Paroxysmal Positional Vertigo (BPPV) and microvasculitis: A comparative study between nasal cytology and pathology
Published on: 24th February, 2020
OCLC Number/Unique Identifier: 8540540513
Purpose: Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vertigo syndrome in otoneurological clinical practice and is characterized by short and paroxysmal objective vertigo crises caused by changes in the position of the head on specific planes of space. Secondary microvasculitis is characterized by inflammatory destruction of the small vessels. Starting from this point, this work is based on the research of correlation between microvasculitis (especially secondary), recurrent BPPV and nasal cytology, an aspect, among other things, poorly documented.
Materials and methods: To evaluate the relationships between recurrent BPPV and secondary microvasculitis, nine patients with this disorder, 5 males and 4 females aged between 25 and 40 years were observed (average age 30.6). Non allergic pains in the small joints and in the anamnesis nothing relevant in the gentiles and collaterals: Evaluated with vestibular audiometric examination, nasal cytology and vascular examination with corneal HRT results. Nasal cytology, in all cases, has documented the presence of rare mast cells. The hemodynamics of the microcirculation with a confocal microscope has revealed blood flow alteration in all subjects.
Discussion: Analyzing the results, both the prevalence of the right side and a close relationship between vasculitis and BPPV could be seen.
Conclusion: The study of the nasal mucosa and the research of inflammatory cells could be fundamental for the study of BPPV in which as we have seen the important biochemical role for the onset of these diseases.
Medical coverage of the 29th “Tour du Faso”
Published on: 7th May, 2019
OCLC Number/Unique Identifier: 8163873543
Purpose: Medical coverage of the 29th “Tour du Faso” primarily aimed to report the experience of the medical coverage of the 2016 International Cycling Tour of Burkina Faso.
Methods: This is a prospective study of the medical coverage of the 2016 International Cycling Tour of Burkina Faso.
Results: During the 12 days of medical coverage, 216 consultations were recorded. The complaints were diversified. From simple asthenia to severe malaria. There were cases of indigestion, gastroenteritis and food allergies.
Conclusion: The medical coverage of a cycling competition requires knowledge of the discipline, expertise in sport and emergency medicine.
Clinical Case: Necrotizing Fasciitis of the neck after surgery of a Mandibular Radicular Cyst
Published on: 24th November, 2017
OCLC Number/Unique Identifier: 7379455745
Necrotizing fasciitis is a quickly progressing soft tissue infection that can be described with diffuse necrosis of subcutaneous tissue and superficial fascia. The cause of this can be infectious process of odontogenic origin, most commonly caused by mixed gram+ and gram- , aerobic and anaerobic microorganisms that are found in patients that are predisposed to infections. In a case of undiagnosed illness, there is a possibility of life threatening complications. This case analysis introduces the diagnostic criteria of the disease and treatment plan, encouraging doctors to devote more attention to prevention of infections.
Percutaneous Closure of Post-myocardial Infarction Ventricular Septal Rupture-experience From a Resource-limited Setup From Eastern Part of India
Published on: 20th June, 2024
Background: Post-infarction ventricular septal rupture (VSR) is a rare but lethal mechanical complication of an acute myocardial infarction (AMI). It results in 90% - 95% mortality within two months of diagnosis without any kind of intervention. Given high surgical mortality, transcatheter closure has emerged as a potential strategy as an alternative to high-risk surgical closure. Indian data on percutaneous device closure of post-AMI-VSR is limited hence we report our resource-limited single-centre experience with different kinds of occluder devices for closure of post-AMI VSR.Methods and results: In this single-centre, retrospective, cohort study, patients who underwent transcatheter closure of post-MI VSR between 2018 and 2024 at Health World hospitals, in Durgapur, West Bengal, were included. The primary outcome was a mortality rate of 30 days. The study population was eleven primary cases of post-MI VSR. The mean age of the population was 61 years. The majority of the patients had anterior wall MI (54.5%) and the remaining had inferior wall MI. Different kinds of devices (ASO, PostMI VSD device, Konar MFO) were used to close VSR. Successful closure was performed in 9 patients (81%) with minimal residual shunt in 2 patients. Out of 9 cases 3 patients expired, one was lost to follow up and the rest are doing well at 30 days follow-up. Conclusion: Transcatheter closure of PMIVSRs can be performed with different kinds of devices with high technical success, relatively low procedural complication rates, and 30 days survival even in a resource-limited setup as an alternative to high-risk surgical closure.
In vitro, Anti-oxidant, and Anti-inflammatory Activity of Kalanchoe pinnata
Published on: 24th January, 2025
Kalanchoe pinnata is a widely recognized medicinal plant known for its antioxidant and anti-inflammatory properties. This study explores its in vitro antioxidant and anti-inflammatory activities, highlighting its potential for pharmaceutical and biomedical applications. The research innovatively assesses its bioactive components using DPPH radical scavenging, nitric oxide inhibition assays, and phenolic content analysis. Results demonstrated significant antioxidant activity with IC50 values comparable to ascorbic acid, along with notable anti-inflammatory effects via nitric oxide inhibition. These findings emphasize Kalanchoe pinnata’s potential as a source for developing antioxidant and anti-inflammatory therapeutics. Further investigation into bioactive compound isolation and mechanistic pathways is recommended to clarify its pharmacological efficacy.
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