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A model of the 2014 Ebola virus: Evidence of West Africa

Published on: 2nd May, 2019

OCLC Number/Unique Identifier: 8164049985

Outbreaks of Ebola virus can cause substantial mortality in affected countries. The largest outbreak of Ebola to date is currently underway in West Africa, with 3944 cases reported as of September 5, 2014. For the sake of deriving a better understanding of the Ebola transmission dynamics, we have undertaken to revisit data from the initial spark of origin of the Ebola virus, which occurred in 1976 in Zaire (now Democratic Republic of Congo). By fitting a mathematical process to time series stratified by disease onset, outcome and source of infection, we have managed to estimate several epidemiological quantities, previously admitted to be too challenging to measure, including hospital and infected community contribution infection to the widespread transmission.
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The review of the relationship between UCP2 and obesity: Focusing on inflammatory-obesity

Published on: 19th January, 2021

OCLC Number/Unique Identifier: 8895645747

Understanding the obesity-related genes may provide future therapeutic strategies to modulate disease progression. UCP2 separates oxidative phosphorylation (OXPHOS) from ATP production in the inner mitochondria. Figure 1 shows the differences among UCP1, 2, 3. The main role of UCP2 is controlling the metabolism of energy in the cells [1-3]. Besides that, the expression of UCP2 is associated with chronic inflammation due to reactive oxygen species (ROS). In this regard, in injured cells and tissues, ROS could be decreased by reducing the proton motor force by the anti-inflammatory effect of UCP2 [4].
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Antifungal Efficacy of Panchgavya Formulations against Rhizoctonia solani: An Incitant of Rice Sheath Blight

Published on: 2nd October, 2024

The main rice-grown crop was found severely affected by sheath blight in the south Gujarat region. Sheath blight of rice symptoms were noticed on leaf blades and the sheath just above the water level. The isolation was done from infected parts and purified by the hyphal tip method on PDA which was maintained at 4 oC. The seven different panchgavya formulations of five cow products such as cow urine, dung, curd, ghee, and milk that designed as PG1, PG2, PG3, PG4, PG5, PG6, and PG7. The PG against test pathogen Rhizoctonia solani in vitro condition by the poisoned food technique and that tested at 2, 4, 6, 8, and 10 percent concentrations. It was observed that panchgavya were able to suppress the growth of R. solani. Among the different formulations, PG1 was significantly effective at all concentrations as compared to other PG formulations against R. solani.
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Kinesio taping in patients with shoulder impingement

Published on: 22nd May, 2019

OCLC Number/Unique Identifier: 8163920703

Study Design: Prospective Observational Study. Background: Physical therapy is one of the primary treatment options for these patients, however, we were unable to identify previously published research that objectively assesses the impact of taping on joint range of motion or on pain levels in patients with SAIS. This gap in the literature motivated the present study. Objectives: To describe the results of the application of neuromuscular taping in patients with subacromial impingement syndrome (SAIS), with respect to their pain levels, joint range of motion, and acromiohumeral distance, assessed via ultrasound. Methods: A prospective series of cases was evaluated at the Hospital Italiano de Buenos Aires between April and September of 2018. Twenty-four patients from age 25 to 65 were invited to participate (9 men and 15 women), all of whom had been diagnosed with rotator cuff tendinopathy, impingement syndrome, or bursitis with positive signs of impingement in the affected shoulder and anterior shoulder pain in flexion. Result: Significant changes in AHD (Figure 2), pain, and anterior flexion were registered after taping. Superficial dermatitis was detected in only two patients, but this did not affect the assessment. Conclusion: In the results obtained by this study, it has been observed that the application of neuromuscular taping using the method described above significantly increases AHD, leading to short-term improvements in pain and joint range of motion.
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Difference in Injury Risk between Male and Female Alpine Skiers: Review of the Literature

Published on: 3rd April, 2024

Alpine skiing is popular at varying levels of competitiveness with many skiers participating recreationally and elite skiers competing in downhill, super-G, giant slalom, slalom, and combined events in the World Cup and in the Winter Olympic Games. The rate of injury in alpine skiing is high both recreationally and competitively and methods to reduce injury rates are needed. Additionally, it is well-established in other sports that the risk of injury for an athlete varies based on gender. The purpose of this review is to determine how injury risk differs for each gender of alpine skier. Injury rates vary throughout the literature but point towards males being at a higher risk for overall injury and upper body injuries while females are at a higher risk for knee injuries. Even the specific knee injuries for which each gender is at risk varies with medial collateral ligament (MCL) injuries more common in males and anterior cruciate ligament (ACL) injuries more common in females. More studies are needed to confirm the differences in injury risks and how these risks may differ across levels of competition, thus allowing regulations and injury prevention methods that may be tailored specifically to the injuries an alpine skier is most susceptible to.
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Statistical Mathematical Analysis of COVID-19 at World Level

Published on: 5th April, 2024

Worldwide, statistical data of people infected by COVID-19 has been taken until March 29, 2023, which, when correlated, showed a predictive logistic  model. The purpose was to determine the predictive model, which was acceptable, in such a way that the proportionality constant and the correlation and determination coefficients are of great importance to estimating epidemiological and pandemic data; coinciding with what was reported by other authors. Bearing in mind that a mathematical model is a mathematical description through a function or equation of a phenomenon in the real world; whose purpose is to understand infections and make predictions for the future. The stages were: to model the number of people infected as a function of time, formulate, and choose the logistic model, determine the model and obtain mathematical conclusions, and make predictions (estimates) about the number of people infected by COVID-19 worldwide. The logistic model was derived to predict the speed of people infected by COVID-19 and the critical time (tc = 733 days) for which the speed was maximum (1694,7209 infected/day). The Pearson correlation coefficient for the time elapsed (t) and the number of people infected (N) worldwide, based on 32 cases, was r = -0.88; the relationship between time and those infected is real, there is a “very strong correlation” between the time elapsed (t) and the number of people infected (N) and 77.03% of the variance in N is explained by t. 
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The Role of Diet Therapy in Reducing the Cardiovascular Disease Risk in a Patient with a Long-Standing and Recurring History of Obesity

Published on: 11th October, 2024

Insulin resistance, often referred to as impaired insulin sensitivity. This clinical case focusses on a woman with insulin resistance and a long-standing and recurring history of obesity to demonstrate how diet therapy can be applied in addition to standard medication therapy.
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Clinically Observable Ocular Manifestations of Axonal Transport

Published on: 25th September, 2023

This report illustrates and provides a novel explanation for post-trabeculectomy improvements in the visual field, cup disc contours, and apparent deepening of an arcuate nerve fiber layer (NFL) defect after trabeculectomy for open-angle glaucoma. These changes are all plausible manifestations of recovered axonal transport and thickening retina, previously thinned by elevated intraocular pressure (IOP). Serial pre-and post-operative clinical fundus photos in case 1(A,B) demonstrate increased prominence of an inferior temporal arcuate nerve fiber layer defect, improved cup disc ratio, and visual field following eye pressure lowering by + 50% after trabeculectomy. Case 2 (C,D) also demonstrates obvious cup disc improvement in post-operative photos with associated improvement in visual field after trabeculectomy and lowering IOP by + 30%. We suggest that elevated IOP suppresses primarily orthograde axonal transport resulting in nerve fiber layer (NFL) thinning that can recover back to normal thickness when IOP is surgically lowered by the magnitude achieved in these two examples.
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Radionuclide contents in yam samples and health risks assessment in Oguta oil producing locality Imo State Nigeria

Published on: 5th April, 2021

OCLC Number/Unique Identifier: 9024345201

Oguta LGA is surrounded by 44 oil wells located around different communities. Preliminary investigations indicated that crude wastes were not properly managed and oil spillage occurred regularly in the LGA. Therefore, assessment of both radionuclide contents in yam matrix and health risks in Oguta was carried out to determine possible radiological health risks associated with improper management of crude wastes, and also evaluate haematological health profile in the LGA for future reference and research. A well calibrated NaI (Tl) detector was deployed for the radiological investigation, and about 5 ml of blood samples were collected from 190 participants each from Oguta and the control LGAs for haematological assessment. Mean activity concentrations due to 40K, 226Ra and 232Th in yam samples from Oguta LGA were 189.99 ± 59.14 Bqkg-1, 23.75 ± 5.69 Bqkg-1 and 30.99 ± 9.51 Bqkg-1, respectively while mean activity concentrations due to natural radionuclides in yam samples from control LGA were 110.40 ± 78.53 Bqkg-1, 10.12 ± 3.34 Bqkg-1 and 18.39 ± 8.74 Bqkg-1 for 40K, 226Ra and 232Th, respectively. Committed effective dose equivalent values in Oguta and the control LGAs were 704.95 ± 183.30 μSvy-1 and 403.65 ± 172.19 μSvy-1, respectively which are less than world average value of 1.1 mSvy-1. Crucially, one-way ANOVA at α0.05 has indicated that effects of radiological parameters due to natural radionuclides in yam from Oguta are significantly different from effects of radiological parameters due to natural radionuclides in yam from the control LGA. However, the percentage contributions of natural radiation exposures to incidence of cancer in Oguta and the control LGAs are just 1.7% and 1.4%, respectively, and haematological investigations have shown that overall health of the communities in the study LGAs has not been compromised due to environmental and human factors. Hence, natural radioactivity may have been elevated in Oguta but the concentration levels are not yet alarming. Radiological health risks could result from consistent exposure to those natural radionuclides in the long term.
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Influence of high frequency rotating magnetic field on the effect of heating magnetic fluid

Published on: 5th April, 2021

OCLC Number/Unique Identifier: 9026744675

The article describes the necessary conditions for the phenomenon of thermal energy release in a magnetic fluid placed in a high-frequency rotating magnetic field. The minimum amplitude of the magnetic field was calculated and the thermal power released (by the rotating spherical nanoparticles in the viscous medium) was estimated. The estimations were based on the assumption that the magnetic relaxation times (τN and τB) and the magnetic field rotation period (τrot) meet the condition: τN>>τrot>>τB. The principle of operation and construction of the device generating a high-frequency rotating magnetic field is described. Preliminary experimental studies were carried out using a magnetic fluid with magnetite nanoparticles that indicated magnetic relaxation as the cause of the released heat. The value of the absorption rate in the experiment and its dependence on the strength of the magnetic field were determined.
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