Alexander G Volkov*, Jewel S Hairston, Darayas Patel and Sergey Sarkisov
Published on: 22nd August, 2023
Cold atmospheric pressure plasma (CAPP) treatment is a highly effective method of protecting seeds, plants, flowers, and trees from diseases and infection and significantly increasing crop yields. Here we found that cold atmospheric pressure He-plasma jet (CAPPJ) can also cause side effects and damage to plants if the plasma exposure time is too long. Reactive oxygen and nitrogen species (RONS), electromagnetic fields, and ultraviolet photons emitted by CAPPJ can cause both positive and negative effects on plants. CAPPJ can interact with biological tissue surfaces. The plasma lamp has no visible side effects on Aloe vera plants, cabbage, and tomatoes. A plasma lamp and a cold atmospheric pressure plasma He-jet cause strong electrical signaling in plants with a very high amplitude with frequencies equal to the frequency of plasma generation. The use of plasma lamps for electrostimulation of biological tissues can help to avoid side processes in biological tissues associated with the generation of RONS, UV photons, and direct interaction with cold plasma. CAPP technology can play an important role in agriculture, medicine, the food industry, chemistry, surface science, material science, and engineering applications without side effects if the plasma exposure is short enough.
We report a case of 79-year-old man who presented to our emergency department (ED) for lipothymia. The patient developed significant bradycardia with hypotension. His EKG objectified a slow atrial fibrillation .the patient rapidly installed a coma. A non-contrast CT brain scan showed a bilateral vertebrobasilar ischemic stroke.
Aim: With the continuing trend in the incidence of diabetic ulcer, the current researches on wound care and healing will bring best and effective practices on wound care and healing among patients suffering from diabetes mellitus.
Methods: This study utilized a systematic review of literatures in light of wound care through Pub Med database with the key words “Diabetes Mellitus,” “wound practices,” “wound healing,” and “systematic review.” The searched literatures were of case reports, interventional studies, and review papers whose main texts were in English.
Results: There were 7,988 published articles yielded from the keywords used and 16 were included in this study. The practiced management and techniques in these literatures focused on comfortable and cost efficient means of wound care and healing with the involvement of group participation than individual plan of care.
Conclusions: There are meager evidences of feasible wound and healing options that needs further studies in resolving wound issues among patients with Diabetes Mellitus. This systematic review establishes the insufficiency of high level of evidence based studies on wound healing in DM patients and brings a track for continuity of rigid studies concerning this topic.
In the paper a methodology that is elaborated for characterization of big-sized chambers of modern and future nuclear fusion reactors is described. It gives an opportunity to define distortions introduced by surroundings, systems and elements of the chamber into the neutron field generated during the reactors’ operation. The procedure is based on two types of experimental techniques supported by MCNP numerical modelling. These two classes are: 1) the neutron activation methods for measuring changes in anisotropy of the “absolute” neutron yields, and 2) the time-of-flight process for determination of neutron spectra deformations. MCNP calculations afterwards give an opportunity to fix just those elements of the surroundings that introduce the main impact in the perturbed neutron field characteristics.
The demand for materials and devices that are capable of controlling heat flux has attracted many interests due to desire to attain new sources of energy and on-chip cooling. Excellent properties of DNA make it as an interesting nanomaterial in future technologies. In this paper, we aim to investigate the thermal flow through two sequence combinations of DNA, e.g, (AT)4 (CG)4 (AT)4 (CG)4 and (CG)8 (AT)8. Two interesting phenomena have been observed respectively. In the first configuration, an oscillatory thermal flux is observed. In this way, an oscillating heat flux from a stationary spatial thermal gradient is provided by varying the gate temperature. In the second configuration, the system behaves as a constant heat current source. The physical mechanism behind each phenomenon is identified. In the first case, it was shown that the transition between thermal positive conductance and negative differential conductance implies oscillatory heat current. In the latter, the discordance between the phonon bands of the two coupled sequences results in constant thermal flow despite of increasing in temperature gradient.
Latent fingerprints are a common source of information for forensic experts and law enforcement agencies. The thin layer chromatography (TLC) plates that are prepared in this work are made with silica gel G powder. Latent fingerprint remnants are made up of secretions from the nose, palm, and sebaceous, apocrine, and eccrine glands (sweat). However, the quest for more versatile and effective techniques persisted, leading to the emergence of innovative approaches like Silica Gel G powder. The silicon atoms are linked to –OH groups at the silica gel’s surface. A latent fingerprint is an imprint left by direct contact with a surface or object that is not apparent to the unaided eye. The advantages of using Silica Gel G powder for latent fingerprint visualization underscore its significance as an innovative technique in forensic science. The latent fingerprints were developed on each of the several substrates using Merck Specialties Private Limited’s white-coloured silica gel G powder. There are several techniques in the literature for creating latent fingerprints. The emergence of Silica Gel G powder in forensic science represents a significant breakthrough in the visualization of latent fingerprints. The process of using Silica Gel G powder for latent fingerprint visualization exemplifies the precision and attention to detail required in forensic investigations.
Background: Pulmonary fibrosis is a clinical problem with an enigmatic etiology with no effective therapy. Current therapies for lung fibrosis are ineffective for progression of lung fibrosis and preventing respiratory failure.
Objectives: The aim of this study is to explore the expression of Desmin, α-smooth muscle actin (α-SMA) and the telomerase subunit: human telomerase reverse transcriptase (h-TERT) in a spectrum of lung tissue samples consist of lung fibrosis, lung cancer, and healthy controls.
Materials and Methods: The expression of Desmin, α-SMA and hTERT were studied in samples of 15 pulmonary fibrosis samples, 16 samples of lung cancer and 14 healthy controls investigated. We evaluated Desmin, α-SMA as well as the expression of components of telomerase (TERT), by methods: RNA Extraction and cDNA synthesis, Real-Time quantitative PCR, Immunohistochemistry, all prepared from lung tissue paraffin blocked.
Results: α-SMA marker detected 1(8.3%) of healthy control and 11(91.7%) of lung fibrosis samples. The difference between groups was significant (p<0.001). Also the difference between healthy control 1(6.7%) and lung cancer 14 (93.3%) for α-SMA marker was a significant (P<0.001). It was a significant difference between healthy control and lung cancer for TERT expression (P=.005). TERT was not positive in any sample of neither healthy control nor lung fibrosis. For TERT, it was a significant difference between lung fibrosis and lung cancer by Fisher’s Exact Test (P=.004). Expression of TERT and α-SMA between small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) was not statistically significant (P=.700, P=0758), respectively.
Conclusions: We recommend more investigation to regard α-SMA, Desmin in patients with lung fibrosis and follow them for possible cancer risk. Also, more study is needed to regard TERT as a marker in lung cancer. Assessment of these markers may have future implication to explain the same way of pathogenesis and carcinogenesis of fibrosis and cancer and for prevention or treatment
The childhood obesity is increased more than three folds in last two decades in developed world. There is nutritional transition seen in the developing world including India. The westernization in diet of the Indian population along with prosperity brings the brunt of overweight and obesity. This has future implications of liver diseases, heart diseases, hypertension, hyperlipidaemia, insulin resistance; malignancies. Mumbai is the prosperous city and an economical capital of India. Also, the rampant use junk food, common outdoor eating’s, no grounds to play for children make the high likelihood that the prevalence of obesity to be higher than rest of the country.
It can profoundly affect children’s physical health, social, and emotional well-being and self-esteem. It is also associated with poor academic performance and a lower quality of life experienced by the child.
One of the best strategies to reduce childhood obesity is to improve the eating and exercise habits of the entire family. Treating and preventing childhood obesity helps protect the child’s health and has tremendous impact on child’s Physical and academic performance.
And hence we at Aastha Bariatrics took initiative and launched ECHO... for a change (‘E’radicating ‘C’Hild ‘H’ood ‘O’besity), a pan Mumbai campaign against childhood obesity.
This campaign was done in 15 high schools across Mumbai, which covered in total of 9000 students.
Mark Taubert, Lorenz Weidhase, Sirak Petros and Henrik Rueffert*
Published on: 17th October, 2018
A 64-year-old woman was referred to our hospital due to progressive dypnoea for the past week, combined with fever and type 1 respiratory failure. White blood cell count and procalcitonin level were normal. The Chest X-ray showed bilateral disseminated pulmonary infiltrates. Within the next 24 hours the patient developed a severe ARDS. A first diagnostic work-up for typical and atypical pathogens as well as serological tests for CMV, RSV, HIV and HSV were negative. Analysis of a second bronchoalveolar lavage fluid revealed Pneumocystis jiroveci DNA. The patient was successfully treated with trimethoprim-sulfamethoxazole and off label use with caspofungin. The cause of the infection was a six week treatment with dexamethasone. The patient developed a toxic epidermal necrolysis during further course, but completely recovered.
Pneumonia with Pneumocystis jirovecii must also be taken into account in non-HIV patients, whenever there are any indications that cellular immunity may be depressed.
A 50-years old female presented with dysarthria, inability to swallow and quadriparesis for three weeks. She had rapid correction of her serum sodium (Na) from 99meq/l to 138meq/l within 24 hours 1 week prior to development of these symptoms. She was diagnosed as a case of Osmotic demyelination syndrome (ODS) formerly known as central pontine myelinolysis (CPM) which was confirmed by MRI. She underwent Plasma Exchange (PE) on the 20th day since her symptoms started and underwent 7 cycles of PE with complete neurological recovery. Pt was discharged with ability to ambulate independently and complete recovery of speech and swallowing. Hence, we report that PE is beneficial in chronic ODS.
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