How Bruguiera gymnorhizza seedlings respond to climate change induced salinity rise?
Published on: 22nd September, 2017
OCLC Number/Unique Identifier: 7286422995
A study was undertaken during August 2017 to evaluate the effect of salinity on chlorophyll a, chlorophyll b, total chlorophyll, and carotenoid and proline contents of hydroponically grown seedlings of Bruguiera gymnorhizza. The primary aim was to observe its tolerance to changing salinity. The selected seedlings were exposed to five different salinity levels (2,5,10,15 and 20psu) for a period of 30 days and observations were done at a regular interval of 7,14,21 and 30 days respectively. The concentrations of chlorophyll exhibited significant positive correlations with salinity (p<0.01). The chlorophyll a:b ratio in the plant varied between 2.39 to 3.71 throughout the period of investigation. The salinity fluctuation did not affect the carotenoid level and proline content in the leaves of the species as evidenced from the insignificant r values. The results show that Bruguiera gymnorhizza of Indian Sundarbans region can tolerate and adapt to high saline condition as witnessed in the central sector of the deltaic complex around the Matla River.
3-Dimensional Versus 2-Dimensional Comparison of Knee Valgus Collapse during Vertical Jump: Clinical Implications for ACL Risk of Injury Assessment
Published on: 21st March, 2017
OCLC Number/Unique Identifier: 7286358320
Time-efficient screening of lower extremity biomechanics to identify potential injurious movement patterns is crucial within athletic medicine settings. When considering biomechanical risk factors for anterior cruciate ligament injuries, several screening tests have been used to assess dynamic knee valgus. Current methods involving 3-dimensional motion capture systems are considered gold standard for such assessment; however, these methods are time consuming and require expensive materials. This study investigated the use of 2-dimentional kinematic evaluation during a standardized vertical jump athletic assessment to screen for potential lower extremity risk of injury. 50 collegiate athletes, 25 male and 25 female, from various sports participated in the study. The vertical jump was chosen because it is a common performance evaluation test that is regularly performed several times a year, providing consistent opportunities for screening while not creating additional obligations for the student athletes. Results showed that the 2-dimentional evaluation method had strong correlations (P<0.0001) with the gold standard 3-dimensional evaluation, suggesting that an accelerated 2-dimentional screening process can be used as a first step to screen for potential injurious lower extremity movement patterns.
Vertebral pain syndrome and physical performance assessing in older women with vertebral fractures
Published on: 17th October, 2017
OCLC Number/Unique Identifier: 7286344789
The purpose of this study was to assess the peculiarities of vertebral pain syndrome, parameters of physical performance and quality of life indices in women of older age depending on the presence of vertebral fractures (VF). This study was performed with participation of 215 women aged 50-89 years old which were divided into two groups: first one-women without any previous osteoporotic fractures (n=143), second group - patients with VF in thoracic and/or lumbar spine (n=72).
The presence and intensity of pain in the thoracic and lumbar spine were evaluated using the 11-component visual analog scale (VAS), physical performance-with following functional tests: 3-, 4- and 15-meter tests (gait speed), static balance (a side-by-side position, a semi-tandem position and a full-tandem position), 8-feet test and «five timed chair stands» (coordination and strength), hand grip strength (by dynamometer), measurement of arterial pressure (systolic and diastolic), heart and respiratory rates, breath holding, chest excursion (mean and on the inhalation and the exhalation), lateral trunk lean, Schober and Thomayer tests.
It was demonstrated that the intensity of vertebral pain (pain at the time of investigation, the most common level of pain, pain in the best periods of the disease) and some physical performance tests (lateral trunk lean and chest excursion (mean index, during the inhalation and exhalation), hand grip strength, 15-meter gait speed test and five-repetition sit-to-stand test) are significantly worse in women with VF than corresponding parameters in persons without fractures. It should be taken into account during the assessment of physical performance and development of rehabilitation programs for older age women with vertebral fractures.
Effect of foot posture on foot-specific health-related quality of life
Published on: 10th January, 2018
OCLC Number/Unique Identifier: 7317601185
The purpose of this study was to determine the relationship between Navicular drop (ND) and Hallux valgus (HV) angles and their effects on foot-specific health related quality of life. Sixty female patients with bilateral HV aged between 32-60 participated in this study. The patients with the HV deformity degree of “2” or “3” according to the Manchester scale were included.
HV angle were obtained from standing (weight bearing) bilateral antero-posterior radiographs. HV angle (A angle), intermetatarsal angle (B angle), hallux interphalangeal angle (C angle) were measured. Subtalar pronation was measured the navicular drop (ND) test. ND test were performed for both feet and recorded in millimeters. Foot-specific health related quality of life was measured using the Manhester-Oxford Foot Questionnaire (MOFQ).
There was a strong positive correlation between the ND qtest and the angles A, B, and C for the right foot (rho=0.749, 0.761 and 0.749 p<0.001, respectively,). There was a strong positive correlation between the MOFQ subscales and the angles A, B, and C for the right foot (p<0.001). There was a strong positive correlation between the MOFQ subscales and the angles A, B, and C for the right foot (p<0.001).
In conclusion, there were relationship between ND, HV angular severity and foot-specific health related quality of life. As the HV angular severity increased, there was greater drop in the navicula and reduction in quality of life.
Seroma formation as a rare complication of lateral epicondylitis release: A case report
Published on: 27th October, 2017
OCLC Number/Unique Identifier: 7286357077
Case: A 45 year old male, >1 year status post left elbow lateral debridement for lateral epicondylitis, presented with a two week history of a progressive, tender mass on the lateral aspect of his left elbow. MRI showed evidence of a defect in the joint capsule, consistent with the formation of a seroma. The patient underwent revision of the left lateral epicondyle debridement with ECRL/EDC tendon repair and capsular reconstruction.
Conclusion: Tendon repair and capsular reconstruction is an effective and successful method for the treatment of a seroma caused by leakage of joint fluid after lateral epicondylar debridement.
Perception of Nutrition and Exercise as a Tool in Controlling Cardiovascular Diseases among the Elderly in Anambra State
Published on: 3rd November, 2017
OCLC Number/Unique Identifier: 7286355386
The research investigated the perception of nutrition and exercise as a tool in controlling Cardiovascular Diseases (CVDs) among elderly civil servants in Anambra State of Nigeria. A total of 250 respondents comprising 150 elderly academic staff Nnamdi Azikiwe University Awka and 100 senior civil servants in the Anambra state civil service, who willingly, volunteered to participate in the study. Their ages ranged between 55-65 years purposively selected. The instrument for data collection was a self-structured questionnaire, with a reliability value of 0.73 using the test retest method. All data collected were subjected to descriptive statistics of frequency, percentages and chi square tested at 0.05 level of significance. Findings from the study showed that nutrition (diet) and exercise have significant effect in the prevention/control of (CVDs) among the elderly. It is therefore recommended that at the civil service secretariats, universities and other establishments/parastatals, should establish high standard eateries (restaurants) where qualified caterers, would regularly provide nutritious diet, at subsidized rate for workers in this category. In order to enable these class of workers have at least one good meal per day, in addition to a mandatory one- work-free afternoon (2.00pm-4.00pm) for routine/regular physical exercises for these class of workers.
Ultrasound conjugated with Laser Therapy in treatment of osteoarthritis: A case study
Published on: 24th January, 2018
OCLC Number/Unique Identifier: 7317653930
Osteoarthritis of the hand is a chronic condition that involves hand joints, but receives less attention. Few studies have investigated the use of ultrasound therapy and laser therapy for the treatment of hand osteoarthritis. The objective was to evaluate the effect of the conjugated treatment of therapeutic ultrasound and laser therapy on the pain and joint function of a patient with hand osteoarthritis. The is case of a woman, 57 years old, with a diagnosis of osteoarthritis on hand for 3 years, presenting constant pain and worsening after manual activities. The pain and function were evaluated, respectively, by Visual Analog Scale (VAS) and Australian Canadian Osteoarthritis Hand Index questionnaire (AUSCAN). After 12 sessions using ultrasound and laser therapy application, there was an expressive improvement in the pain and functional indexes of the patient. The combined application of therapeutic ultrasound and laser therapy, through the unified field action of the therapies used, proved to be efficient in reducing pain and improving the functionality.
Influence of elbow angle on the reliability and validity of bioelectrical impedance analysis
Published on: 23rd November, 2017
OCLC Number/Unique Identifier: 7286351075
Hand-to-hand bioelectrical impedance (HH BIA) is a low-cost method to estimate percent body fat (%BF). The BIA method is consistently reliable, but questions on validity remain. We have observed anecdotally that elbow position can render consistently different measures of %BF while using HH BIA, thus leading to the question: Does elbow angle influence the validity of measures derived using HH BIA? The purpose of this study was to assess the effect of elbow position (i.e., IN=flexed to 90° versus OUT=fully extended) on the reliability of HH BIA on 44 male and 24 female healthy adults (age=21±2 yrs, BMI=23±3). An additional aim was to assess the validity of the HH BIA %BF on a subset of subjects (n=12) using air displacement plethysmography (BOD POD®) as the criterion measure. The IN position was ~4%BF lower than the OUT position for HH BIA (p=0.05, effect size=0.67). Measures of %BF for both trials for the IN [intraclass correlation coefficient (ICC)=0.99, coefficient of variation (CV)=2.99%] and OUT (ICC=0.99, CV=1.48%) conditions were highly reliable. On the subsample, the OUT (18.3±6.7 %BF) position exceeded both the IN (14.5±7.4 %BF) and the BOD POD® (16.1±7.8 %BF) measures (p<0.05); however, IN and BOD POD® measures of %BF did not differ (p=0.21). These findings support that HH BIA is a reliable measure at both elbow positions; however, %BF estimations vary considerably (~4%) with respect to the criterion measure depending on elbow position. The OUT position was found to overestimate criteria %BF. Further research may reveal an optimum elbow angle position for HH BIA estimates of %BF.
3-D Current Density and Magnetic Field of 3-D MR Scanner Gradient Coil
Published on: 28th June, 2024
The topic of this paper is to describe the 3-D current density in the windings of a 3-D coil, which fills the volume between two coaxial cylinders at a precisely defined distance from each other, and which serves to generate a magnetic field gradient in the center of the cylinder axis. The 3-D current density is considered an unknown input quantity, which is calculated from the known gradient magnetic field output. It is an inverse problem in mathematics, where the direct problems are the calculation of unknown output quantities based on known input quantities. Fourier series expansion methods in the context of cylindrical coordinates were used to describe the 3-D current density. In that case, Bessel functions are used as development components. The current densities, at each point in space, were lined up to represent current lines. Each power line is associated with a coil winding through which a current of a certain strength flows. After that, the principle of discretization of coil windings was applied. Each winding is divided into a large number of elementary segments that were considered as current elements, which create, based on Bio-Savar's law, an elementary magnetic field. In this way, the total, continuous magnetic field is broken into many elementary components, which come from different current elements. An important result of this process is that each current element can be controlled independently by a current source. This means that the output magnetic field of the gradient can be controlled by current sources, which are the input sizes, and this is what is at the core of the topic of this paper.
Unmasking Renal Complications of Immunotherapy: A Case of Nivolumab-induced FSGS
Published on: 7th February, 2025
Immune Checkpoint Inhibitors (ICPIs), while revolutionizing cancer therapy through potentiation of anti-tumour responses via targeted blockade of T-lymphocyte inhibitory receptors, are associated with immune-related adverse events (irAEs), including diverse renal manifestations. This report presents a case of a 69-year-old male with urothelial carcinoma who developed Acute Kidney Injury (AKI) and nephrotic-range proteinuria following initiation of nivolumab, an anti-PD1 antibody, necessitating renal biopsy to clarify the aetiology. The biopsy revealed Focal Segmental Glomerulosclerosis (FSGS) with endotheliopathy, suggesting a direct ICPI-induced glomerular injury. This case underscores the need for heightened awareness of ICPI-associated glomerular disease, alongside more common renal adverse events such as Acute Interstitial Nephritis (AIN), and for the need for renal biopsy in such cases. While the incidence of ICPI-associated AKI is approximately 17%, and AIN is a more frequent finding, FSGS and other glomerular pathologies should also be considered. Current treatment for such renal events involves discontinuation of the ICPI agent and initiation of immunosuppression with glucocorticoids. The management of these cases requires prompt detection, timely diagnosis, and often interdisciplinary collaboration, thus highlighting the need for more case reports, research, and better treatment strategies.
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