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The paper presents and develops the issue of Cumulative Effect Assessment (CEA) in the Environmental Impact Assessment (EIA) screening procedure established by the State and Regional regulations In Italy. In the period 2001-15 in the territory of the Venice province (north east Italy, Veneto region) n. 328 projects (and the related environmental preliminary/definitive studies) were applied to competent Authorities (6% to the State, 39% to the Region and 55% to the Province). All the Environmental Impact Studies (EISs) and Environmental Preliminary Studies (EPSs) referring to the this territory officially applied to competent Authorities in the period 2001-2010, have been analysed with focus on the identification and assessment of cumulative effects (CEs); the projects considered and analysed for this purpose comprise a total of n. 181 EIA screening and ordinary procedures; the remaining 147 projects in the period 2011-15 (for a total of 328) are here considered only for statistical reason to an update assessment of project typologies in the same territory. The methodology applied for the analysis of the sample of environmental studies in the period 2001-10 refers to that presented by Cooper and Sheate (2002) with modifications. The investigation has been developed looking for the way in which the topic is performed by practitioners in the environmental studies as from qualitative as well as quantitative point of view. Specific attention has been paid to waste management plants which are always subject to EIA screening procedure since 2008 according to Directive 97/11/EEC and in case to the whole EIA procedure. The approach proposed by Lombardia Region (North Italy; 2010) for EIA screening procedure of waste management plants has been applied to identify CEs and modified according to the characteristics of the considered territory; it allows the performance of the project-based approach and must be completed with a regional-based approach (Dubè, 2003). The proposed approach can be useful in case of waste management and IPPC (Integrated Pollution Prevention and Control, Directive 96/61/EEC, amended with Directives 2008/1/EC and 2010/75/EU) plants to define the financial warranties required for the authorization of operative activity of the plants to cover potential environmental damages produced in cases of accidents and other conditions as required in Europe (art. 14 Directive 2004/35/EC on environmental liability). Several project categories were chosen and their EISs analysed as an exemplificative case according to the potential generation of cumulative impacts and the characteristics of the territory. With reference to the completed procedures where the competent Authority presented a final judgement, it has been observed that the CEA has been seldom developed due to not compulsory legal requirements as already observed by Burris and Canter (1997). Moreover, when it is considered, the methodology is limited and not systemized. Indices of impact have been identified according to emission for the main environmental components focussed with the analysis of the pressure factors of the plants. The study points out the need to analyse and evaluate the cumulative effects (CEs) at a strategic level (within the Strategic Environmental Assessment-SEA- procedure) with a view to preparing the study for EIA/EPS framework procedure for the projects derived from the corresponding plan/program. A sound knowledge of the considered territory and in particular of its pressure sources is of main importance for CEA assessment and impacts’ prevention. Geographic Information Sytesm (GIS) application is strongly needed for pressure sources’ census and control data storing

For over twenty years, following the creation of space stations, MIR first and then the ISS (International Space Station) men (3 to 6) live and succeed each other continuously about 300 - 400 km of altitude to make scientific experiments. For this reason sending men into space has become an activity “almost banal or regular “but this remains potentially a very dangerous environment for the adapted manon Earth and thus requires medical monitoring to ensure the health of astronauts and the persistence of their ability during their mission. In general, the medical benefits on Earth of space conquest go far beyond envy and the need for man to discover the cosmos but to develop many tools medicines to also offer solutions for all living beings on Earth!

Cerebral Autoregulation (CA)-directed therapy, or optimal cerebral perfusion pressure (CPPopt)-targeted therapy, is a tailored bedside method of resuscitation used in critical care that aims to achieve and maintain the CPPopt, to fit the precise cerebral hemodynamics and metabolic demand. Different processes and multiple tools are available to conduct a CA-directed therapy in acute brain-damaged adult admitted into critical care settings, but literature is limited and primarily focused on traumatic brain injury; however, for other brain conditions. By this scope review, we aim to describe the main procedures used by authors to achieve a CA-directed therapy, as well as its acquisition methods and its usefulness in acute non-traumatic brain-damaged adult in neurocritical care.

The examination and the survey of how a person moves, particularly the way of life of walking and running. It entails studying and quantifying a person's gait in terms of their stride length, cadence, foot position, and movement of various body joints. Wearable technology makes it possible to monitor the gait pattern continually while moving about freely. The direction line, gait line, foot line, foot angle, principle line, step length, step breadth, and displacement value obtained from the gyro and accelerated sensors coupled to the shank and thigh are all used to analyze the gait pattern. There has been a lot of research on this method of recognizing people by the way they walk.The two most crucial facts are that OpenPose, a 2D multi-person posture estimation library, can detect 135 critical body locations without the requirement for fiducial markers, and that smartphone cameras can detect the gait pattern without the use of physical markers. In addition, lower extremity sagittal joint angles, spatiotemporal gait parameters, and timings of gait events were independently determined for motion capture. Gait analysis systems use portable, readily available cameras to measure gait characteristics. The pace of gait, length of steps, time of steps, cadence of steps, and the period of stance are the most crucial factors. Recently, the top standard for the examination of gait was used to evaluate the schemes based on two camera usage to evaluate the framework of different gait patterns.The precision of the examination of SCA is being increased by data scientists through the development of AI-based computer algorithms. To increase individualization, Bertillon measured the body and faces of several convicts in 1883.

Micronutrients are critical components of an athlete’s diet, affecting both performance and cardiovascular health. This review summarizes current studies on the importance of micronutrients in sports cardiology, focusing on their effects on energy metabolism, antioxidant defense, and cardiac function. Key findings emphasize the relevance of micronutrient sufficiency in improving athletic performance and avoiding long-term health issues linked to strenuous training programs. Micronutrients like B vitamins help energy generation pathways, while antioxidants like C and E reduce exercise-induced oxidative damage. Minerals like magnesium and iron are important for muscle function and oxygen delivery, which are required for endurance and recovery. Effective nutritional practices include balancing food intake and, if required, supplementing under medical supervision to address individual needs and enhance performance results. Future research paths will focus on individualized nutrition techniques based on genetic and metabolic profiles, allowing for more precise food recommendations for athletes. Collaboration between sports medicine and nutrition disciplines is critical for establishing evidence-based practices and improving cardiovascular health in athletes.

It is known today that psycho-trauma and PTSD cause different levels of mental and social dysfunction. Human spirituality and capacity to meet further life difficulties become severely damaged. There is wide accepted attitude today that in holistic approach in process of healing PTSD and psycho-trauma is necessary to include other professionals from community resource regarding needs of trauma victims. In Bosnia and Herzegovina after very severe war (1992-1995) as mental health professionals, we are faced with increasing number of different mental health disorders as result of severe trauma experiences. Regarding community based care orientation it is necessary to include and religion professionals. According national and religious background of majority of our population in Tuzla Canton that is Muslim, we meet spiritual needs of our clients as needs for Islamic explanation of life and death meaning. Our clients need to talk about spiritual issues in daily therapy and to practice daily religious rituals. Regarding that in this paper we tried to interface Islamic principles and it’s beneficial toward psycho-trauma and PTSD, as well as Muslim perspectives in attempt to apply spiritual practice in therapeutic tools for better efficacy in spiritual healing of mental dysfunction’s of believers who survived severe trauma, especially war trauma.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbursts began at the end of 2019, which imposed a serious crisis on public health and the economy all over the world. To date, there is no antiviral drug available for SARS-CoV-2, and hence vaccination is the most preferred method to prevent people from getting attacked by this virus, especially for those who are at high risk. To counter coronavirus-2, there are various types of vaccines, which are being used, such as live attenuated vaccines, killed or inactivated vaccines, recombinant vaccines, mRNA vaccines, recombinant vector vaccines, and DNA vaccines. Novavax data shows that the vaccine is effective against severe diseases caused by B.1.351. The Pfizer-BioNTech and AstraZeneca vaccines show evidence of some protection against P.1. Due to the immune response, the Human body can recognize and protect itself against harmful foreign substances such as bacteria, viruses, and microorganisms. The immune system protects our body from these harmful substances by identifying them as antigens. Virus-infected cells release many chemicals such as chemokines and cytokines for the initiation of immune response. To control the pandemic situation, herd immunity is required by the immunization of a critical mass of the world population at once. In this review article, we have made an analysis of the immune response of the human body to SARS-CoV-2 infection, different types, and modes of action of SARS-CoV-2 vaccines along with the current status of vaccines.

Wheat bran and groundnut shell powder have been used to study the mechanism of diclofenac sodium adsorption from aqueous solution using batch as well as column modes and maximum uptake is 84.3% for wheat bran and 82.4% for groundnut shell powder at pH 6, drug concentration 1mg/L at 298 K for 30min. Isotherm and error analysis reveals that Freundlich and Langmuir isotherms fitted well. Kinetic studies show that the adsorption process follows second-order kinetics and thermodynamic study shows endothermic adsorption process. Column adsorption study is important for industrial scale adsorption and column studies have been carried out using vertical bed and sequential bed adsorption columns at pH 6 which is the optimum pH for maximum adsorption for batch experiments. Vertical and sequential bed columns setup is simple and economical which provides flow under gravity. The effect of varying inlet feed concentration and flow rate on the breakthrough and exhaustion time of columns has been studied to determine the bed capacities of both columns. Thomas model and Yoon-Nelson models fitted well with experimental data for continuous flow column studies.

Background: Intravascular Leiomyomatosis (IVL) is an often misdiagnosed rare benign mesenchymal tumor characterized by the presence of vascular extension and invasion of smooth muscle cells in a serpiginous-like pattern, first originating in uterine smooth muscle cells. Its growth pattern can involve both ovarian veins, the inferior vena cava, and even reach the right atrium/ventricle in 45% of the cases. The incidence has been reported to be 0.25 to 0.40% of patients with uterine leiomyoma, with about 300 cases reported in the literature. Also, since the tumor is hormone-dependent, most affected individuals are premenopausal women in middle age. Optimal treatment for IVL is complete surgical removal with hysterectomy and oophorectomy, independent of stage. The most frequent perioperative complications are hemorrhage due to tumoral hypervascularization, embolism, and the usual laparotomy complications. We present the case of a 51-year-old female with IVL stage 3 with complete single-stage surgical resolution.

Background: The search for antimalarial molecules from plants necessitates comparative studies of ethnomedicinal antimalarial plants to quickly identify those that may be used in further search. Therefore, the median lethal dose, LD50, and the antiplasmodial activities of the methanol extracts of the stem barks of Anthocleista vogelii, Bligha sapida, Voacanga africana, and the leaf of Momordica charantia were evaluated against Plasmodium berghei berghei-infected mice using prophylactic, chemosuppressive, and curative models to compare their activities and identify the most active for further evaluation. Methods: The plant materials were collected, authenticated, and voucher specimens were deposited at the Faculty of Pharmacy Herbarium, OAU, Ile-Ife. They were separately macerated in methanol, and the median lethal dose, LD50 determined using Lorke’s method. The percentage parasitaemia, percentage reduction, chemosuppression and clearance, survival time, and percentage survivor of each, in the three models of antiplasmodial test against Plasmodium berghei berghei infected mice were assessed. Pyrimethamine and Chloroquine were positive controls, while normal saline was a negative control. One-way analysis of variance (ANOVA) followed by Student Newman-Keuls post hoc test (p < 0.05) was used for the analysis of data. Results and Conclusion: The lowest prophylactic ED50 and ED90 values 304 and 624 mg/kg of AV, comparable chemosuppressive ED50 values of all extracts and the significantly (p < 0.05) lower values of ED50 and ED90 of MC and VA in the curative assay can guide the selection of the plant extract(s) for further antimalarial evaluation.