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Role of pollen morphology in taxonomy and detection of adulterations in crud drugs

Published on: 2nd April, 2020

OCLC Number/Unique Identifier: 8577732918

Present paper communicates 42 species of angiosperms depicting characteristics of pollen grains as shape, color, exine ornamentations, and type of apertures. Pollen morphological characters are very important in plant identifications in field. Pollen surface features plays significant role in taxonomy and detection of crud drugs. Firsthand information is gathered from field and provided in this research article.
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Amine Functionalized Graphene Quantum Dots as a Smart Nano Antibacterial Agent

Published on: 13th December, 2024

Conventional antibiotics are resisted by bacteria at an increasing rate, prompting studies into the development of alternate antibiotic agents. This work demonstrates the fabrication and characterization of amine functionalized graphene quantum dots (af-GQDs) with starting materials of graphene oxide, ammonia, and hydrogen peroxide by chemical oxidation and hydrothermal methods. The synthesized af-GQDs were characterized using analytical techniques such as UV-vis, fluorescence, FTIR, Raman spectroscopy, and morphological studies through TEM. TEM images showed that af-GQDs have smooth surface morphology with porous in nature and are spherical in shape with particle size less than 20 nm. The prepared af-GQDs show a quantum yield of 26.32%. A growth inhibition test was performed on E. coli and S. aureus for the prepared af-GQDs at different increasing concentrations. The minimum inhibitory concentration for the prepared af-GQDs on E. coli was found to be 55 μg/mL and for S. aureus was found to be 35 μg/mL. Percentage cell viability studies were performed on HeLa and Jukart cells for 24 hours at different concentrations. Both cells showed maximum cell viability percentage at the initial concentration. At higher concentrations, the cell viability is decreased for both cells but the Jukart cells show a minimum percentage of cell viability at higher concentrations than the HeLa cells.
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Misoprostol Usage in the Kingdom of Bahrain: A Retrospective Study

Published on: 7th November, 2025

Introduction: The document introduces the topic of medical termination of pregnancy (MTP) using misoprostol, a synthetic prostaglandin E1 analogue. It discusses the advantages and challenges of this method, and the research gap in the Gulf region and the Middle East. It also states the aim of the study, which is to evaluate the safety, efficacy, and acceptability of misoprostol for MTP in Bahrain. Methods: The document describes the study design, data source, and inclusion criteria. It explains that the data was collected from the Hope system in King Hamad University Hospital and included women in the first and second trimester of pregnancy who were undergoing MTP as per the FIGO protocol. It also mentions the statistical analysis that was used to compare the outcomes of different regimens, dosages, and routes of administration of misoprostol. Results: The document reports the main findings of the study, such as the success and failure rates of MTP, the association between previous deliveries and MTP outcomes, the optimal number and route of misoprostol doses, the length of hospital stay, and the incidence of complications. It also presents some figures to illustrate the results. Discussion: The document interprets the results and compares them with previous studies. It highlights the high efficacy of the sublingual route of misoprostol but also acknowledges the side effects and limitations of this route. It suggests that two doses of 600mcg or 800mcg of misoprostol are sufficient for MTP. It also identifies the strengths and weaknesses of the study and proposes some future directions for research. Conclusion: The document concludes that the study provides a better understanding of the outcomes of misoprostol for MTP in a controlled environment. It asserts that misoprostol is a safe and effective option for women seeking abortion in the first and second trimester, especially in low-resource settings. It also emphasizes the need for evidence-based guidelines and counseling for misoprostol use.
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Phytochemical Compounds and the Antifungal Activity of Centaurium pulchellum Ethanol Extracts in Iraq

Published on: 25th June, 2024

The current study included a variety of phytochemical substances that were extracted from Centaurium pulchellum and showed a wide range of medicinal properties from the plant's reproductive and vegetative parts against the pathogenic fungus Aspergillus flavus. The vegetative and reproductive components of Centaurium pulchellum were subjected to (GC-MS) analysis for phytochemical study. The data indicated that fungal activity was the highest. Four extract concentrations of 5, 10, 15, and 20 mg/ml were utilized in the investigation, and the diameter of the colonies measured at each concentration was 90.00, 36.00, 28.00, 18.00, and 0.00 mm, respectively.Nine bioactive phytochemical compounds were found in Centaurium pulchellum's vegetative and reproductive portions, according to GC-MS analysis of the chemicals. Another study reported phytochemical substances that: 1-H-Imidazole-2-carboxaldehyde, 1-methyl-;Acetaminophen; n-Hexadecanoic acid; Mercaptoacetic acid, 2TMS derivative; 1.2,3-Dimethyl-5-(trifluoromethyl)-1,4-benzenediol #; Mercaptoethanol, 2TMS derivative-; Bis-(3,5,5-trimethylhexyl) phthalate Tetrakis(trimethylsilyl) orthosilicate #;- 1.1-Isopropoxy-3,3,3-trimethyl-1-[(trimethylsilyl)oxy]disiloxanyl tris(trimethylsilyl) orthosilicate #.
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Gallstone Ileus: A Rare Case of Intestinal Obstruction, Presented in a Chronic Kidney Disease Patient on Haemodialysis

Published on: 5th February, 2025

The prevalence of gallbladder stones is higher in Chronic Kidney Disease (CKD) patients and it has been shown to increase with the advancement of the disease stage, from 7.7% in stage 1% to 21.3% in stage 5. Gallstone ileus is a rare complication which presents in just 0.3% - 0.5% of patients with cholelithiasis. A 61-year-old female patient, with a known case of CKD on maintenance hemodialysis, (thrice a week) with primary disease of hypertensive and diabetic nephropathy; presented with multiple episodes of loose stool, vomiting, and diffuse abdominal pain for 2 days. Abdomen Ultrasonography (USG) was suggestive of intestinal obstruction. CT abdomen with oral contrast revealed grossly dilated jejuna loops with air-fluid levels and transition zone in the pelvis, in distal jejunal loops/proximal ileum with ovoid intraluminal filling defect cystic polyp and collapsed bowel loops. The patient underwent exploratory laparotomy in view of persistent small bowel obstruction. Resection and anastomosis of the mass-bearing small bowel segment were performed. On cutting and opening the specimen, a large stone was revealed. This gallstone was causing bowel obstruction-gall stone ileus. A gallstone 2.6 cm x 2.1 cm has traversed through a cholecysto-duodenal fistula and got stuck in the proximal ileum, causing small bowel obstruction. The lesson learned is uraemia can cause gastrointestinal symptoms like anorexia, abdominal pain, vomiting, and ileus and hence mimic serious differentials of the acute abdomen like gallstone ileus. Thus no stone should be left unturned especially when the prevalance of gallstones is high in chronic kidney disease patients.
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In silico analysis and characterization of fresh water fish ATPases and homology modelling

Published on: 11th October, 2017

OCLC Number/Unique Identifier: 7317598561

ATPases is known to be a crucial in many biological activities of organisms. In this study, physicochemical properties and modeling of ATPases protein of fish was analysed using In silico approach. ATPases a protein selected from fish species, including Gold fish (Carassius auratus auratus), Zebra fish (Hypancistrus zebra), White fishes (Coregonus autumnalis), Grass carp (Ctenopharyngodon idella) and Anabas testudineus (Koi) were used in this study. Physicochemical characteristics showed with molecular weight (25045.58-25148.57Da), theoretical isoelectric point (9.30-9.97), extinction coefficient(26470-34950), aliphatic index(147.31-150.35), instability index(32.84-42.67), total number of negatively charged residues and positively charged residues (5/7-6/8), and grand average of hydropathicity (1.014-1.151) were computed. All proteins were classified as transmembrane proteins. In secondary structure prediction, all proteins were composed of random coils as predominant, followed by extended strands, alpha helix and beta turn. Three dimensional structure of protein were predicted and verified as good structures. All model structures were evaluated being accepted and reliable based on structural evaluation and stereo chemical analysis.
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Microcystic Meningioma: Atypical Meningioma Revisited. Rare Case Report with Review of Literature

Published on: 10th April, 2025

Meningiomas, classical extra-axial dural-based tumors of the meninges, have well-documented classical imaging features and signs on CT and MRI. Most meningiomas are classical lesions with prompt diagnosis on imaging and generally exhibit benign outcomes with slow growth patterns. The latest WHO classification of tumors in 2021 has classified 15 subtypes of meningiomas, and while classical meningiomas are WHO Grade 1 tumors, grading between varying subtypes varies between WHO Grades 1 and 3. The microcystic meningioma is a rare and atypical subtype of meningioma that has been sparsely documented in literature. In this case report, we revisit this rare subtype of meningioma with a brief review of literature.
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The Effect of Shoulder Immobilization Position on Outcomes Following Rotator Cuff Repair: A Scoping Review

Published on: 20th August, 2024

Introduction: There has been growing interest in determining the influence of post-operative immobilization posture and rehabilitation protocol on healing rates and clinical outcomes. Current consensus calls for the use of an immobilization device post-operatively, which commonly comes in the form of a standard sling or an abduction brace with the arm positioned in varying degrees of abduction. There is a lack of high-level evidence in the literature to recommend one type of immobilization device or arm position over another. Objectives: This study aimed to summarize the current clinical and biomechanical evidence for the optimal postoperative positioning and bracing of the arm following arthroscopic rotator cuff repair. Methods: A comprehensive search of the electronic databases EMBASE, MEDLINE, and PubMed was performed using a combination of the following keywords and medical subject heading (MeSH) terms: ‘arthroscopic’, ‘rotator cuff repair’, ‘sling’, ‘brace’ and ‘immobilization’. This systematic review was conducted following the Preferred Reporting for Systematic Reviews and Meta-analysis (PRIMSA) guidelines. Two reviewers performed an independent assessment of the methodological quality of each eligible clinical study using the Methodological Index for Non-Randomized Studies (MINORS).Results: Based on current biomechanical evidence, placement of the arm into an abducted position following rotator cuff repair was found to be favorable. An abduction angle of 30° was associated with lower strain on the repair while maintaining appropriate contact pressure at the footprint. However, the use of an abduction brace did not result in a clinically significant improvement in long-term PROM, ROM, and re-tear rates when compared to a traditional sling in clinical studies.Conclusion: Despite observing favorable outcomes with abduction bracing after rotator cuff repair in biomechanical studies these findings were not reproduced in clinical studies. However, current clinical studies are comprised of small sample sizes, varying tear sizes, and significant heterogeneity in both, the degree of abduction and forearm rotation. Future studies should be directed towards prospectively investigating the effect of immobilization position among patients with similar rotator cuff tear sizes.
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Multipurpose Antioxidants based on Food Industry Waste: Production and Properties Evaluation

Published on: 20th June, 2025

Some preliminary results of studies on the assessment of the possibilities and prospects for obtaining products with a high Antioxidant Activity Index (AOA) from the waste of the coffee beverage production industry - "silver skin" (SC, silverskin, CS) are presented.The obtained data on the extraction of SC with aqueous-alcoholic extractants, the effect of extraction conditions on the yield of extracts, and extractive substances are discussed. It is reported on the production of dry powders of extracts that retain their properties during long-term storage.Data on the antioxidant properties of both liquid and dry forms of extracts are presented and good AOA of the studied objects is noted in comparison with the "standard" antioxidant - rosemary extract, and it is also shown that the AOA of dry forms of extracts can be increased by doping with synergists - polyphenols of natural genesis. The antioxidant activity of the obtained compositions was studied on real objects - animal fats and natural dyes, the results of which confirmed the prospects of the studied antioxidants (AO) for practical purposes.
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A Rare Case of Cytomegalovirus Colitis Mimicking Colon Adenocarcinoma in an Immunocompetent Patient

Published on: 11th July, 2025

Cytomegalovirus (CMV) colitis is classically seen in immunocompromised individuals, such as those with HIV, organ transplants, or receiving immunosuppressive therapy. It is exceedingly rare in immunocompetent patients and can pose a diagnostic challenge, especially when it presents as a mass-like lesion mimicking colon cancer. We report a case of a 78-year-old immunocompetent male who presented with hematochezia and was found to have a bleeding cecal mass initially suspicious for adenocarcinoma. Subsequent histopathology revealed CMV colitis. This case emphasizes the importance of considering CMV colitis in the differential diagnosis of colonic masses, even in immunocompetent hosts.
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