Primary Diffuse Leptomeningeal Melanocytosis: A Rare and Challenging Diagnosis
Published on: 17th April, 2024
Primary melanocytic neoplasms of the central nervous system are rare entities and can present in different clinical forms with mild and non-specific symptoms (such as headache and tinnitus) to severe and limiting symptoms (focal deficits and intracranial hypertension), mimicking the most diverse pathologies. In addition to the peculiar changes in imaging tests, diagnosis is always a challenge given the multitude of possible differential diagnoses, including aseptic meningitis. Given this, we bring here the case of a 59-year-old patient who attended care due to headache and vertigo followed by involvement of the cranial nerves and spinal cord, corroborated by physical examination and imaging study suggesting diffuse involvement of the meninges, which was subsequently confirmed by anatomopathological examination as a primary melanocytic neoplasm of the central nervous system but ended up dying due to complications resulting from late diagnosis. The objective of this work is to raise awareness about the possibility of this pathology as a differential diagnosis in these cases where there are often frustrating clinical manifestations but with changes in imaging tests, to enable an early diagnosis and consequently the possibility of a better therapeutic result, in addition to a brief review of the propaedeutic findings of this pathology.
Designing a Community Health Worker (CHW) Certificate Training that Centers Marginalized Youth’s Health and Wellness
Published on: 23rd April, 2024
The genesis of the youth Community Health Worker (CHW) and Citizen/Community Science (CS) training is rooted in interdisciplinary research and the lived experiences of families in Chicago and Urbana-Champaign. Dr. Mendenhall and colleagues’ (Drs. Robinson, Roberts and Rodriquez-Zas) South Chicago’s Black Mothers’ Resiliency Project provide dinsights into Black women’s experiences with genomics, trauma, and community science. Black women’s testimonies highlighted the health impacts of living in neighborhoods with high levels of gun violence and the resilience strategies they employ. This led to the development of a youth-centered CHW and CS training program, aimed at addressing health disparities. The program trained high school students and young adults (up to age 24) as CHWs and CSs, focusing on the objectives of (1) embedding culturally competent health workers in marginalized communities; (2) amplifying community voices; (3) collecting, analyzing, and quantifying observational data to inform policy decision-making; (4) amplifying community voices in healthcare discussions and (5) creating community health care worker training certification for youth. Over three years, the program trained over 50 participants, incorporating elements of wellness, art, and entrepreneurship.Based on ethnographic notes participants reported increases in wellness such as reduced anxiety and increased empowerment. The program’s long-term goals include creating employment opportunities for graduates and contributing to improved community health outcomes. This initiative represents a step towards addressing racial trauma and promoting community healing through youth-led innovation and empowerment.
On Friedman equation, quadratic laws and the geometry of our universe
Published on: 25th June, 2021
OCLC Number/Unique Identifier: 9272395207
Einstein’s special and general relativity revolutionized physics. The predictions of general relativity are Strong Lensing, Weak Lensing, Microlensing, Black Holes, Relativistic Jets, A Gravitational Vortex, Gravitational Waves, The Sun Delaying Radio Signals, Proof from Orbiting Earth, Expansion of the universe. The density of the universe determines the geometry and fate of the universe. According to Freedman’s equations of general relativity published in 1922 and 1924, the geometry of the universe may be closed, open and flat. It all depends upon the curvature of the universe also. Various results of Cosmic Microwave Background Radiation (CMBR), NASA’s Wilkinson Microwave Anisotropy Probe (WMAP), and ESA’s Planck spacecraft probes found that our universe is flat within a margin of 0.4% error. In this short work, by applying the laws of quadratic equations, we attempt to show that OUR UNIVERSE IS FLAT.
Experiences of patients with lung cancer receiving concurrent chemo-radiotherapy
Published on: 23rd March, 2021
OCLC Number/Unique Identifier: 8982640075
Purpose: In an aspect of qualitative treatment, this research gathered lung cancer patients’ actual experiences to understand deeply, such as their expectation for treatment results, their difficulties during treatment, and their various requests to their family and medical teams.
Methods: From May to June 2013, semi-structured interviews were conducted with 9 lung cancer patients. Data were collected through a tape-recorded in-depth interview. The analysis of the data was made through the qualitative method.
Results: 124 themes regarding the experience were found. From these 35 concepts, 24 subcategories were emerged. The core category was enduring hardship of the treatment with the hope for full recovery. Six categories included ‘Wishing to be cured but concern about recurrence’, ‘Receiving radiation treatment with pleasure and difficult at the same time’. ‘Being sorry for their family’s full support and trying to stand alone‘, ‘Having confidence in their medical team’, ‘regretting for their old days’, and ‘Wanting to live a long life without illness and pain’.
Conclusion: The results of this study would help oncology nurses to understand the lung cancer patients receiving concurrent chemo-radiotherapy (CCRT) and to develop a quality of life improvement program for physical, psychosocial, and spiritual aspects of nursing.
Ambivalent sexist attitudes of young adolescents from the province of Jaén: Regarding the use of sexual and/or pornographic content on the internet
Published on: 26th March, 2021
OCLC Number/Unique Identifier: 9031337467
Knowing the possible origin of sexist attitudes in adolescents is essential when educating them to avoid gender violence derived from them. Nurses have an important role in education for the health of children and adolescents, so we must study the risk factors that lead to these attitudes and how to prevent them. Some studies such as Landripet, et al. have undertaken to study the association between frequency of pornography use and preference for violent and coercive content in male adolescents. Sexism and pornography use have been associated by various authors. Hostile sexism is the most obvious and traditional form, based on the supposed inferiority or difference of women as a group. According to benevolent sexism, women are understood as deserving of affection, respect and protection, as long as they are limited to certain traditional feminine roles. The second is even more difficult to detect. Our aim in this work is to evaluate ambivalent sexist attitudes in young adolescents in the province of Jaén and check whether there is a relationship between use of pornography and sexual content, and the kinds of sexism studied, in order to be able to prevent these attitudes as nurses through health education. The final sample was made up of 150 participants from all school years, belonging to the same secondary school, 74 male and 76 female. They were aged between 12 and 18 years old. One of the conclusions of this work has been that the use of new technologies is in addition starting at even younger ages due to the situation of online teaching due to the pandemic, and it has been observed that age at first use is a determining factor.
Post-vaccine immunity against hepatitis B in Moroccan children
Published on: 2nd September, 2022
OCLC Number/Unique Identifier: 9617320088
Background: Hepatitis B is a major public health issue worldwide. Immunization of infants against this disease has been effective in Morocco since 1999. However, evaluation of post-vaccination response is rarely performed in our setting. The purpose of this study was to evaluate immunity against HBV in fully vaccinated children in the city of Marrakech in Morocco and to investigate the factors influencing the level of post-vaccination immunity. Methods: A descriptive cross-sectional study was conducted on fully vaccinated children who have medical and vaccination records, from three primary healthcare centers in Marrakech. Children with anti-HBs antibody levels between 10 and 100 IU/L were considered moderately immune, and those with antibody levels above 100 IU/L as highly immune, while those with antibody levels below 10 IU/L were considered non-immune. Results: Of the 123 children recruited, 114 (92.7%) had protective anti-HBs antibody titers, of which 37 (30%) were moderately immunized and 77 (62.7%) were highly immunized, and nine (7.3%) were non-immune. Age, birth weight, vaccine type, and time since the previous dose have all been significantly associated with the degree of post-vaccination immunity. Anti-HBs antibody levels were not significantly related to factors potentially linked to post-vaccination non-response, such as chronic disease, immunosuppressive medication and others.Conclusion: Our findings denote that the HBV vaccine used in The Moroccan Expanded Program on Immunization (EPI) is effective against HBV. Nevertheless, in non-responders, corrective actions such as re-vaccination and monitoring of post-vaccination anti-HBs antibody levels should be implemented.
Millian´s ear sign: Bilateral ear erythema
Published on: 9th March, 2021
OCLC Number/Unique Identifier: 8982640801
A 79 years old woman presented with one-day history of pain, redness, pain and swelling without discharge in her left ear, later her right ear started with the same symptoms as in her contralateral ear spreading around the scalp and the forehead (Figure 1), she denied fever, or other constitutional symptoms.
Adult Neurogenesis: A Review of Current Perspectives and Implications for Neuroscience Research
Published on: 12th November, 2024
Background: The study of new neuron formation in the adult brain has sparked controversy and ignited interest among scientists in recent times, these include its occurrence and location in the adult human brain, functional significance, variation in study methods, translation from animal model to human, and ethical challenges involving neural stem cell research. Aim: To provide a comprehensive understanding of adult neurogenesis, functional significance, and challenges and explore the latest advances in the study of adult neurogenesis. Methodology: An extensive and systematic search of electronic databases (Medline, Scopus, Web of Science) was conducted using keywords related to adult neurogenesis and techniques involved in its study. Results: The mechanism of adult neurogenesis was found to occur in specific brain regions such as the subgranular zone of the dentate gyrus and subventricular zone of the lateral ventricle. Adult neurogenesis is vital neural plasticity, providing a potential mechanism for the brain to adapt and reorganize in response to environmental cues and experiences. Cutting-edge research and sophisticated imaging techniques, such as two-photon microscopy, MRI, optogenetic, and stem-cell-based therapies have provided deeper insight into the study of adult neurogenesis. Conclusion: The study of neurogenesis is important for understanding nervous system development, physiology, pathology, and exploring neuroplasticity. Its advancement is challenged by some ethical concerns regarding embryonic, pluripotent stem cells, and the need for safe, and noninvasive study methods. Although recent breakthroughs in neuroimaging, microscopic techniques, and genetic tools are aiding real-time study of adult neurogenesis.
Total aortic occlusion associated with SARS-CoV-2 (COVID-19) infection: Video Image
Published on: 16th April, 2021
OCLC Number/Unique Identifier: 9026739489
Acute pulmonary damage and vascular coagulopathy appear to be frequent in patients with SARS-CoV-2 infection relation to corona-virus. The inflammatory process accompanying the infection and excessive coagulation state is one of the most important causes of patient loss.
Ocular manifestations in a case of progeroid syndrome
Published on: 11th November, 2021
OCLC Number/Unique Identifier: 9335773745
Progeria syndromes are very rare genetic diseases characterized by premature aging changes. There are several phenotypes and variables noted in literature in some cases difficult to specifically classify a specific syndrome. It occurs due to mutation in DNA repair genes. The most common ocular findings are loss of eyebrow and eyelashes, brow ptosis, lid margin changes, entropion, Meibomian gland dysfunction, severe dry eye, corneal opacity, cataract, poor mydriasis, and rod-cone dystrophy. We report this case with all the above ocular manifestations in 19year old teenager with additional finding being retinal detachment.
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