Clinico-epidemiological characteristics and survival outcome of patients with hypertensive crisis at Kassala Hospital, Eastern Sudan
Published on: 31st October, 2018
OCLC Number/Unique Identifier: 7923823434
Introduction: Hypertensive crisis (HC) is recognized consequence of inadequate blood pressure (BP) control. A hypertensive crisis is further divided into hypertensive emergency (HT-E) and hypertensive urgency (HT-U).
Method: Using a cross-sectional hospital-based study design, patients who had been diagnosed as having HC between January and October 2017 were consecutively recruited in the study. The criteria proposed by the Seventh Joint National Committee were used for the definition of HC.
Result: A total of 81 (.81%) patients newly diagnosed as having HC were enrolled in the study. Of these patients, 50 (61.7 %) patients met criteria for HT-E, while 31 (38.3%) patients had HT-U. Renal impairment (16%), stroke (30.8%), acute coronary syndrome (13.6%) and heart failure (22.2%) were predominant complications associated with HT-E. Out of 81 study subjects, 13 (16%) patients died. Although there was no significant difference in residence, history of smoking, Diabetes mellitus and history of alcohol consumption between groups, old age (P=.o22), male gender(.046), history of hypertension(.007), history of non-governmental employee(.003), poor compliance (p=.002) and high case fatality rate (p=.041) were significantly associated with hypertensive emergency (HT-E).
Conclusion: This study showed that HT-E has high case fatality rate among patients admitted with hypertensive crisis at kassala teaching Hospital. Therefore early detection of hypertension and appropriate management are the main stay for reducing morbidity and mortality among patients with hypertensive crisis.
Survival of Free and Encapsulated Probiotics in Healthy Gummy Candy as a Carrier for Probiotic Capsules
Published on: 1st October, 2024
Probiotic gummy candy is an innovative food that can be used as a carrier to deliver probiotics. This study aimed to manufacture healthy gummy candy (HGC) as a carrier for probiotic capsules. The ingredients' effect on the viability of probiotic capsules and free cells was evaluated for 48 days under refrigerated conditions. Also, the textural properties, overall acceptability of products, and physicochemical properties were tested. The encapsulation probiotics in sodium alginate and chitosan provided a high efficiency of 88.16%. At the same time, the encapsulated cells-based HGC (HGC-C) had higher counts of probiotics than free cells-based HGC, and it remained above the 3 log CFU/g at the end of the 48-day storage period in HGC-C, while the free cells reached zero at 30 days. The HGC product showed a low hardness value and high antioxidant capacity as well as, and the colour coordinates for the product showed more yellow, with an intense red colour. Using mango pulp and probiotics in gummy candies is an innovative and viable alternative to the confectionery industry; therefore, combining fruits as a source of prebiotics and probiotic bacteria could be a promising formula for probiotics gummy supplement preparation.
Equine Anti-Thymocyte Globulin (ATGAM) administration in patient with previous rabbit Anti-Thymocyte Globulin (Thymoglobulin) induced serum sickness: A case report
Published on: 23rd March, 2018
OCLC Number/Unique Identifier: 7666273824
Thymoglobulin is a rabbit-derived anti-thymocyte antibody directed at T-cells and commonly used for induction immunosuppression therapy in solid organ transplantation, especially in immunologically high risk kidney transplant recipients. Despite its frequent use and efficacy, the heterologous makeup of thymoglobulin can induce the immune system resulting in serum sickness which typically presents with rash, fever, fatigue, and poly-arthralgia in the weeks following drug exposure. ATGAM is another anti-thymocyte antibody, targeting the same epitopes, but differs from thymoglobulin by the animal in which the preparations are generated (equine vs. rabbit). Herein, we present a case of a patient with a known history of thymoglobulin-induced serum sickness, who presented with evidence of acute cellular and vascular rejection at their 12-month post-operative visit. Given their immunologically high risk status, they were successfully treated with ATGAM with improvement in their rejection and kidney function. To the author’s knowledge, this is the first case report of successful administration of ATGAM in a patient with a documented history of thymoglobulin induced serum sickness, demonstrating a possible treatment option for acute rejection in patients with reactions to thymoglobulin.
Drinking-water Quality Assessment in Selective Schools from the Mount Lebanon
Published on: 2nd April, 2024
The present study aims to assess and compare the quality of drinking water according to WHO Standards and then illustrate the resulting diseases. Eight samples have been taken from selective different schools in the Mount Lebanon Region. The laboratory tests of the collected samples were performed to determine various physical (e.g., temperature, pH, electrical conductivity, etc.), chemical (Ca+2, Cl-, Fe, Mg2+, NO3, Na+, SO2-4), and microbial such as E. coli, coliform, and non-coliform. Several techniques were used for the analysis including Atomic Absorption Spectrometry, Flame Photometer, and Total Organic Carbon (TOC). The resulting water quality was compared with the standard limits. Each school has different defects according to specific contamination that existed. To save local residents and according to the results of this study, regular monitoring for water quality was proposed; besides more water filtration plants should be installed to provide safe drinking for children’s health.
Cessation of Menstruation during Pregnancy: Overview
Published on: 9th September, 2024
Vaginal bleeding during pregnancy can often be frightening for women. However, such bleeding does not always indicate a serious problem. This type of bleeding occurs routinely, especially in the first 12 weeks of pregnancy. A significant proportion of women who experience bleeding during pregnancy go on to give birth to healthy babies. Despite this, women who frequently experience bleeding problems at different stages of pregnancy may need to take this situation seriously. A critical approach is important both from the gynecologist and from the pregnant woman.
Metal-carbon mesocomposites application possibilities as the medicine magnetic transport within an organism
Published on: 11th December, 2020
OCLC Number/Unique Identifier: 8872659069
The paper is dedicated to the consideration of the metal-carbon mesocomposites application possibilities for the medicine magnetic transport. This trend is determined by correspondent peculiarities of content and structure of mesoscopic composites. The main peculiarities of these nanosized particles are the following: a) the presence of unpaired electrons on the carbon shell; b) the structure of carbon shell from poly acetylene and carbine fragments; c) the atomic magnetic moment of inner metal is equaled to more than 1–3 μB. The creation of reactive mesoscopic materials with regulated magnetic characteristics which can find application as medicine magnetic transport within an organism is very topical. The present investigation has fundamental character. It’s based on the ideas concerning to the change of metal-carbon mesocomposites reactivity. The use is possible as metal-carbon mesocomposites both and they are modified analogously.
Clinically Observable Ocular Manifestations of Axonal Transport
Published on: 25th September, 2023
This report illustrates and provides a novel explanation for post-trabeculectomy improvements in the visual field, cup disc contours, and apparent deepening of an arcuate nerve fiber layer (NFL) defect after trabeculectomy for open-angle glaucoma. These changes are all plausible manifestations of recovered axonal transport and thickening retina, previously thinned by elevated intraocular pressure (IOP). Serial pre-and post-operative clinical fundus photos in case 1(A,B) demonstrate increased prominence of an inferior temporal arcuate nerve fiber layer defect, improved cup disc ratio, and visual field following eye pressure lowering by + 50% after trabeculectomy. Case 2 (C,D) also demonstrates obvious cup disc improvement in post-operative photos with associated improvement in visual field after trabeculectomy and lowering IOP by + 30%. We suggest that elevated IOP suppresses primarily orthograde axonal transport resulting in nerve fiber layer (NFL) thinning that can recover back to normal thickness when IOP is surgically lowered by the magnitude achieved in these two examples.
Prolonged Latency in Previable PPROM in Twin Pregnancies: A Case Series
Published on: 18th October, 2024
Previable Preterm Premature Rupture of Membranes (PPROM) before 24 weeks of gestation in dichorionic diamniotic (DCDA) twin pregnancies is a rare and challenging obstetric complication. Three cases are presented in this case series, all involving prolonged latency periods of 74, 98, and 158 days following membrane rupture. The management strategy employed was expectant, utilizing antibiotic prophylaxis and close monitoring to prevent infection. Neonatal outcomes varied, with pulmonary hypoplasia and respiratory distress observed in some cases. One twin from Case 2 died due to sepsis, while the remaining twins in all three instances survived after extended neonatal intensive care. This series highlights the potential for extended latency and favorable outcomes in select cases, though neonatal morbidity remains a significant risk, underscoring the need for individualized counseling and vigilant care.
The Clinical Pregnancy and Live Birth Following Transfer of One Arrested Embryo: A Case Report
Published on: 22nd October, 2024
Background: One of the problems in vitro fertilization (IVF) treatment for infertility is the high frequency of embryo developmental arrest in the preimplantation stages. Arrested embryos were not selected for transfer and were usually discarded. Case report: We present a case of clinical pregnancy and live birth following IVF treatment and transfer of one arrested embryo. A 31-year-old woman with unexplained infertility underwent IVF treatment. Using the IVF procedure, 7 embryos were produced which were frozen on day 3. In order to embryo transfer in the blastocyst stage, two embryos were thawed and cultured for 2 days. After thawing, one of them was not suitable for transfer and another embryo was arrested at the 10-12 cell stage. Discussion: The Clinical pregnancy and live birth happened after the transfer of an arrested embryo on day 5.Conclusion: This case showed that arrested embryos may resume growth after the transfer to the uterus and result in a successful pregnancy and live birth.
About Efficiency of High-order Harmonic Generation in Attosecond Physics
Published on: 29th October, 2024
For the first time, the interaction between Hydrogen atom and Free-Electron Lasers (FEL) is simulated. The conversion efficiency of High-order Harmonic Generation (HHG) can be enhanced by utilizing a two-color free electron laser with frequency multiplication. It is found that the conversion efficiency of HHG is improved to the largest extent when fourth-fold frequency multiplication is introduced into two-color FEL. The microscopic mechanism of improving the efficiency of HHG is analyzed and discussed.
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