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Obstetric Renal Failure: Causes, Prognosis, and Evolution

Published on: 8th August, 2024

The incidence of obstetric acute renal failure remains significant in developing countries. The aim of our study is to define the risk factors involved in the occurrence of ARF during pregnancy or during the immediate postpartum period and to evaluate its evolutionary profile in terms of epidemiology, etiopathogenesis, and therapeutic management over the years in Morocco. This is a retrospective study conducted in the maternal-infant resuscitation service of the Ibn Rochd University Hospital of Casablanca, over the period from January 2020 to August 2023, including 95 patients. The current incidence in our series over this period was 22.2%. The mean age of our population was 33 ± 7.74 years [18-43 years], 67.3% of patients were in the gestational period, compared to 33.7% in the immediate postpartum period. Fourteen patients were primiparous (8.6%), 27.4% had a history of miscarriage, and 10.7% had a history of pre-eclampsia. Oligo-anuria was initially identified in 24 patients. The most frequent etiology was pre-eclampsia (56.7%), followed by hemorrhage (27%) and sepsis (19.3%). The evolution was marked by recourse to hemodialysis in 62% of cases, with a maternal mortality of 26%. The existence of heart disease, the context of pre-eclampsia, and the use of diuretics and vasoactive drugs were significantly correlated with maternal survival. No factor was correlated with secondary recovery from ARF. The development of health structures and the optimization of screening strategies are the keywords for prevention.
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A Case of Good Efficacy of Tolvaptan in a Patient with Markedly Enlarged Polycystic Kidney

Published on: 20th August, 2024

A 61-year-old patient with autosomal dominant polycystic kidney disease (Irazabal class 1E) in whom renal function had decreased and kidney size had increased over the past 3 years (change in serum creatinine, 1.3 mg/dL to 1.5 mg/dL; change in total kidney volume, 5632 cm3 to 7301 cm3) was treated with tolvaptan 60 mg/day. After 8 years of tolvaptan treatment, serum creatinine remained at 1.51 mg/dL, and total kidney volume was at 6812 cm3. Adequate salt intake and good weight control may have resulted in good outcomes, even in patients with treatment-resistant giant cystic kidney disease.
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Prevalence of Cognitive Impairment in Dialysis Patients in Gauteng Province, South Africa

Published on: 26th August, 2024

Introduction: Cognitive impairment is defined as a new deficit in at least two areas of cognitive functioning. These may include disturbances in memory, executive functioning, attention or speed of information processing, perceptual motor abilities, or language. It has been shown that cognitive impairment is associated with the severity of kidney disease. Methods: The study was a descriptive research design, with participants purposively sampled from the general chronic kidney disease population which included haemodialysis and peritoneal dialysis patients at Steve Biko Academic Hospital in Pretoria, Gauteng Province, South Africa. Hundred and fifty-one participants (76 hemodialysis & 75 peritoneal dialysis patients), 58% were males, and 42% were females aged 19-61 years. To establish the prevalence of cognitive impairment by testing the level of cognition the Mini-Mental State Examination was utilized to provide a brief screening test to quantitatively assess the cognitive abilities and cognitive changes of patients while on dialysis. Results: Ninety-nine percent (99%) of the recruited population reported no cognitive impairment, irrespective of dialysis modality, demographic characteristics, and socio-economic status. Conclusion: Despite the findings highlighting that the majority of the chronic kidney disease population at Steve Biko Academic Hospital reported no cognitive impairment, it is crucial to increase awareness of the potential effects of cognitive impairment on daily activities, quality of life, and treatment adherence. Early detection and management of cognitive impairment can significantly impact the quality of life and adherence to treatment among these patients. Further research is needed to understand the prevalence and impact of cognitive impairment in different populations and to develop effective interventions for its prevention and management.
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An Overview of Familial Hypocalciuric Hypercalcemia

Published on: 26th August, 2024

Familial hypocalciuric hypercalcemia (FHH) is one of the rare reasons for hypercalcemia. FHH is an autosomal dominant disease that is inheritable. The most common calcium sensitive receptors (CaSR) develop because of the inactivation of. In addition, they also develop due to the function loss of AP2S1 and GNA11. The FHH sickness is characterized by hypercalcemia, hypocalciuria, the regular or increased level of the parathyroid hormone, and normal renal function. The symptoms of hypercalcemia are usually not observed. It is often diagnosed by calculating the calcium/creatine clearance ratio of a 24-hour urine sample, and then genetically looking at it. FHH is usually a benign disorder, and when symptomatic and rarely complications develop, calcimimetics are used or parathyroidectomy can be performed. In conclusion, FHH is a benign and genetically transmitted, moderate cause of hypercalcemia. It is rare and usually asymptomatic.
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Computational Simulation of Phase-Molecular Separation-DNA/RNA-Related Function Based on Gene Ontology using Combination of Computational Fluid Dynamics, Machine Learning and Membrane Systems

Published on: 21st May, 2025

Our evaluation and its outcomes/outcomes/hints spotlight that gaining a (having to do with measuring matters with numbers) knowledge of the proteome company in living cells, and its outcomes/consequences/tips for the (introduction and production/ organization of objects) of condensates and MLOs, is a critical assignment that the section separation field wishes to face/address. Our findings that dosage-sensitive (tiny chemical meeting commands interior of living things), insufficient (tiny chemical meeting commands internal of living things) and homologs especially, are overrepresented amongst human LLPS drivers, spotlight furthermore the needed component of preserving the mobile (oversupply/huge quantity) of the (bearing on everyone or issue) DNA/RNA merchandise at a great degree well suited with tightly managed LLPS conduct, to keep away from extreme (diseases/the have a look at of diseases) that unexpected errors in any direction may also cause. In-depth close interest of the records on DNA/RNA concentrations used in the LLPS experiments assisting our excessive self-belief dataset of human driver DNA/RNA s laid the uncertainties related with defining the frame-shape-related meaningful ranges of this essential restriction/guiding principle that leads and controls condensate (introduction and production/ organization of items), and recommended how those uncertainties can be lessened (something awful) and (ultimately) shortened.Graphical abstract: Computational Simulation of Phase-Molecular Separation-DNA/RNA-Related Function Based on Gene Ontology Using Combination of Computational Fluid Dynamics, Machine Learning and Membrane Systems.
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Age Pyramid Assessment of Commercially Important Fishes, Cirrhinus mrigala and Oreochromis niloticus, from the Tropical Yamuna River, India

Published on: 10th July, 2025

Fish are important organisms as they indicate the ecological and environmental processes and the producer-consumer interactions. The fish samples of Cirrhinus mrigala and Oreochromis niloticus were collected from the Yamuna River at Allahabad (now Prayagraj), India, from August 2011 to July 2012. During the study period, 335 specimens of Cirrhinus mrigala and 516 specimens of Oreochromis niloticus were examined for the estimation of the age pyramid. The age groups varied from 0+ to 10+, and a heavy bottom or broad-based age pyramid was recorded in C. mrigala. The age groups varied from 0+ to 6+, and Urn shaped age pyramid was recorded in O. niloticus. The age group 2+ dominated by virtue of numbers in the lower stretch of the Yamuna River in both species of stock.
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Non-adherence to Drug Therapy for Hypertension is Critical and Underestimated in Mexican Patients: A Study from the First Contact Level

Published on: 10th July, 2025

Adherence, in a healthcare context, refers to the extent to which a person’s behavior aligns with recommendations from a healthcare provider. This can involve taking medication as prescribed, following a specific diet, or adhering to lifestyle changes. Although it is known that adherence is critical and requires a special approach to health, in Mexico, there are few studies on this issue. We confirm the information collected from 786 patients using an original questionnaire (AFEC) in Spanish, previously validated. Perfect adherence was detected in only 179 (22.8%), good adherence in 334 (42.5%), and nonadherence in 452 (57.5%). The age, obesity, and number of comorbidities were significantly associated with non-adherence (p < 0.05). Special strategies to approach this critical problem in health need to be reconsidered in Mexico. Non-adherence may help explain the low control rate of Mexican patients and the high rate of cardiovascular mortality.
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Comparison of Rhodium, Vanadium, Cobalt, Inconel & Silver Emitter Self-Powered Neutron Detectors: Literature Review Article

Published on: 7th October, 2024

Self-Powered Neutron Detectors (SPNDs) are in use as in-core Neutron Fluence Detectors in Nuclear Power Plants. Though the detectors are simple in design and have a common structure for the same application, there are various types of emitters (neutron-sensitive electrodes) that make SPNDs categorized into different types. There are various SPNDs in application at different types of nuclear power reactors. SPND emitters are chosen based on their characteristics/behavior in the neutron & gamma flux environment in the reactor core. A detailed Literature Review was done on five different types of SPNDs. This paper focuses on the physics behind the operation, characteristics, and review of Vanadium, Rhodium, Inconel, and Cobalt & Silver emitter-based SPNDs. A comparison study was done by a literature review on these detectors.
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Cyberbullying: A narrative review

Published on: 21st August, 2018

OCLC Number/Unique Identifier: 7844628407

A literature search was conducted using PubMed and PsycINFO to locate cyberbullying research that was published during the last 4 years. In this narrative review, cyberbullying research is briefly summarized and critiqued. The review is focused on the varying definitions and characteristics of cyberbullies, victims and bystanders. Highly variable prevalence rates have been reported for cyberbullies, victims and bystanders as a function of age, gender, country, size of the social network and socioeconomic factors. In addition, the effects of cyberbullying are reviewed including the frequent suicide attempts along with risk factors/predictors of cyberbullying which include previous cyberbullying, excessive internet use and lack of empathy, anger, narcissism and authoritarian/permissive parenting. To reflect the recent literature, special attention is given to the studies on victims of bullying. Research on cyberbullies and on prevention/intervention programs for bullying is extremely limited despite the increasing prevalence of bullying and the rapidly accumulating literature. Methodological limitations include the primary focus on the prevalence of bullying and on the victims of bullying. Longitudinal, multivariate studies are needed to identify profiles on risk factors for bullying that can inform prevention programs.
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Investigation on Theileria lestoquardi infection among sheep and goats in Nyala, South Darfur State, Sudan

Published on: 6th September, 2017

OCLC Number/Unique Identifier: 7325431938

This study was conducted in Nyala, South Darfur State, Sudan during August-September 2015 to study the seroprevalence of ovine and caprine theileriosis and to identify the tick infesting sheep and goats. For this purpose, total of 150 samples (ticks, blood smear and sera) were collected from sheep (n=61) and goats (n=89) of different age groups, breed and both sex. Three age groups were included: less than one-year-old, one-two years-old and more than two-year-old. Two diagnostic techniques were used, blood smears, and indirect fluorescent antibody test (IFAT). Out of 150 samples, 9 (6%) were positive for Theileria spp. piroplasms in blood smears, and 81 (54%) were positive for Theileria lestoquardi antibodies. Out of 61 sheep, 3 (4.9%) were positive for Theileria spp. piroplasms, and 25 (41%) were positive for T. lestoquardi antibodies. Out of 89 goats, 6 (6.7%) were positive for Theileria spp. piroplasms, and 56 (62.9%) were positive for T. lestoquardi antibodies. The highest prevalence of T. lestoquardi was recorded among sheep and goats more than two-year-old. Two genera and 4 species of ticks were infested sheep and goats. These included Rhipicephalus evertsi evertsi, R. s. sanguineus, Amblyomma variegatum and A. lepidum. The study concluded that the malignant ovine theileriosis is endemic in Nyala town.
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