Computational Simulation of Phase-Molecular Separation-DNA/RNA-Related Function Based on Gene Ontology using Combination of Computational Fluid Dynamics, Machine Learning and Membrane Systems
Published on: 21st May, 2025
Our evaluation and its outcomes/outcomes/hints spotlight that gaining a (having to do with measuring matters with numbers) knowledge of the proteome company in living cells, and its outcomes/consequences/tips for the (introduction and production/ organization of objects) of condensates and MLOs, is a critical assignment that the section separation field wishes to face/address. Our findings that dosage-sensitive (tiny chemical meeting commands interior of living things), insufficient (tiny chemical meeting commands internal of living things) and homologs especially, are overrepresented amongst human LLPS drivers, spotlight furthermore the needed component of preserving the mobile (oversupply/huge quantity) of the (bearing on everyone or issue) DNA/RNA merchandise at a great degree well suited with tightly managed LLPS conduct, to keep away from extreme (diseases/the have a look at of diseases) that unexpected errors in any direction may also cause. In-depth close interest of the records on DNA/RNA concentrations used in the LLPS experiments assisting our excessive self-belief dataset of human driver DNA/RNA s laid the uncertainties related with defining the frame-shape-related meaningful ranges of this essential restriction/guiding principle that leads and controls condensate (introduction and production/ organization of items), and recommended how those uncertainties can be lessened (something awful) and (ultimately) shortened.Graphical abstract: Computational Simulation of Phase-Molecular Separation-DNA/RNA-Related Function Based on Gene Ontology Using Combination of Computational Fluid Dynamics, Machine Learning and Membrane Systems.
The Effects of Pharmacological Carbonic Anhydrase Suppression on Defence Responses of Potato Leaves To Phytophthora Infestans
Published on: 3rd March, 2017
OCLC Number/Unique Identifier: 7286357029
In this study we proposed carbonic anhydrase (CA) as an important element of basal resistance during the potato (Solanum tuberosum L.)-Phytophthora infestans interaction. We found a different β-CA expression pattern in incompatible vs. compatible systems correlated in time with CA enzyme activity. Resistant potato leaves supplied with dorzolamide (an inhibitor of carbonate CA activity) and challenged with the pathogen showed an elevated nitric oxide (NO) synthesis, which was the most evident during the early phase of NO burst (at 3 hpi) during hypersensitive response (HR). In vitro application of dorzolamide and effective inhibitors of NO synthesis confirmed the implication of CA activity in NO metabolism during potato defense. To clarify how suppression of CA carbonate activity translates into the complexity of NO-related responses leading to potato resistance or susceptibility to an oomycete pathogen we analysed expression of NPR, PR1, and PAL.
Taken together, pharmacological damping of CA activity revealed a functional link between CA and NO-dependent signaling in potato defense against P. infestans manifested by accelerated NO formation and a modified salicylic acid defense pathway. The dorzolamide-mediated effective responses for basal resistance also delayed symptoms of late blight in the susceptible potato cultivar, without overcoming HR formation in the resistant one.
Antagonistic features displayed by Plant Growth Promoting Rhizobacteria (PGPR): A Review
Published on: 2nd June, 2017
OCLC Number/Unique Identifier: 7286429206
Soil dwelling bacteria able to colonize plant roots and closely associated soil are referred to as rhizobacteria. A wide range of rhizobacteria has the ability to promote plant growth directly by producing phytohormone and nutrients; and indirectly by controlling plant pathogen. These beneficial bacteria are known as plant growth promoting rhizobacteria (PGPR). PGPR control phytopathogens by producing chemicals that could damage pathogen cells, removing pathogen specific nutrients from the environment, or inducing resistance against pathogen in plant body. Antagonistic bacteria specifically damage pathogens by producing lytic enzymes, antibiotics and bacteriocins; and excluding pathogen from plant environment by siderophores oriented iron chelation. This review highlights the antagonistic feature of PGPR. Application of antagonistic bacteria as biopesticides is an attractive alternate of chemical pesticides. Chemical pesticides are non-targeted and cause pollution during its synthesis as well as at the site of application. Antagonistic bacteria could be used as biopesticides and biofertilizers for better plant health and growth improvement.
Artificial Intelligence (AI) in the Chemical Field: Innovation and Risk Evaluation
Published on: 15th August, 2025
This work aims to verify the various uses of AI in chemical settings and the benefits and risks of using this innovative technology.AI tools make it possible to have a powerful instrument in study or research, as well as in various chemical disciplines.After a review of some interesting scientific literature related to some interesting uses of AI and the risks involved, the results of an experimental project involved the use of a famous free AI CHATBOT (question and answer).The articles reported are involved with some benefits of AI use, but also related to the specific risks.Crucial in this world is that the results provided must be the right ones, without relevant error or the so-called “hallucinations”.The results of a specific experimental project using a free AI chatbot show errors in providing one. Chemical structure: The final human control of the AI results can be a useful method to use in a safe way for this technology today.
Physiological impact of Zinc nanoparticle on germination of rice (Oryza sativa L) seed
Published on: 29th August, 2017
OCLC Number/Unique Identifier: 7286344217
Nanoparticles affects growth and development of Plant. Zinc is an important micronutrient that regulates various physiological responses in plant. Application of nanoparticles for modulating plants physiological response is a recent practice. Zinc nanoparticles has been widely used in industry for several decades. However, no significant work had been made on its potential use in agriculture. Understanding physiological effect of Zn NP on rice seed germination could suggest the basis for its prospective application in agriculture to improve plant growth. In the present experiment effect of Zn NP was studied in Kmj-6-1-1 which is a commonly growing rice cultivar of Karimganj district of Assam, India. An exposure to Zn NP (0 mg/L, 5mg/L,10mg/L, 15mg/L, 20mg/L & 50mg/L) caused significant changes in radicle and plumule length , mass ( fresh & dry mass) and seed moisture content in rice. Antioxidant enzymes like guaiacol peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD) and gluthathione reductase (GR) also increased due to ZnNP treatment. This suggest that Zn NP may significantly alters antioxidant metabolism during rice seed germination. In conclusion, Zn NP protected rice plants from ROS damage by improving levels of antioxidant enzyme activities during germination. As a consequence the Zn NP treated seeds, showed better potential for germination. Further, genomic analysis of germinating rice seeds are needed to elucidate the molecular mechanisms by which Zn NP modulates germination process in rice.
Assessment of Albino Beech Supremacy to Pigmented Beech Proves to Be A Better Environmental Condition Bioindicator
Published on: 2nd September, 2025
The research was conducted in southern Serbia, at an altitude of 600 meters, in a beech stand, on a dwarf albino specimen furher usually called Absiente pigmente fagus or just Absiente pigmente. Soil sampling and analysis were carried out at depths of 0-10 cm, 11-20 cm, and 21-30 cm. Laboratory tests included determination of the textural composition of the soil, total humus content, total nitrogen, total phosphorus and potassium, the sum of absorbed base cations, determination of hydrolytic acidity, and both active and substitutional acidity. The soil was found to have a sandy textural composition, with a strong to very strong acidic reaction and a low degree of saturation with base cations. It was further determined to be highly humic, well-supplied with total nitrogen and plant-available potassium, but poorly supplied with phosphorus. Chemical composition analyses of the leaves were simultaneously conducted on both pigmented and non-pigmented leaves. The composition of 15 macro and microelements was examined. The results showed that their concentration in albino leaves was 30% - 50% higher, except in the case of Se. The presence of heavy metals such as cadmium, chromium, and nickel was significantly higher in the non-pigmented beech tissue compared to the green tissue (38.56% for Cd, 22.97% for Cr, and 44.89% for Ni). The research was conducted for the purpose of heavy metal extraction from the soil and green restoration, and it shall continue to this end.
A Case Report of Hepatic Rupture Associated with Hellp Syndrome
Published on: 17th September, 2025
HELLP syndrome is a severe variant of preeclampsia, characterized by hemolysis, elevated liver enzymes, and low platelet count, often resulting in significant maternal and fetal morbidity. One of its most catastrophic but rare complications is hepatic rupture, typically secondary to the development of a subcapsular liver hematoma. This case report describes a patient with hepatic rupture associated with HELLP syndrome, managed at the Leonor Mendes de Barros Maternity Hospital in São Paulo.
Non-chemical control of Armillaria mellea infection of Prunus persica
Published on: 4th July, 2019
OCLC Number/Unique Identifier: 8186251364
Peaches, Prunus persica were planted as grafted saplings in an avocado orchard previously infested with Armillaria mellea (Vahl) P.Kumm. Trees were planted in large or small holes with or without fresh yardwaste chips added as an amendment and with or without a Trichoderma biocontrol product sprayed into the hole. Trees were monitored for six years -- growth and mortality was tabulated. Six years later 40% of the trees had died from the disease. Trees planted in a large hole were more likely to survive than in a smaller hole (P=0.07) and trees in large holes with fresh organic matter added were the most likely to survive (P=0.04). Trichoderma sprays in the planting hole did not increase survival rates. While growth was initially retarded by adding fresh yardwaste to the hole, in later years none of the treatments affected growth rates.
Avermectins: The promising solution to control plant parasitic nematodes
Published on: 13th September, 2019
OCLC Number/Unique Identifier: 8282451461
Abamectin and emamectin are members of avermectin family which categorized as very effective but in the same time are toxic naturally. Most of products in this family are utilized as pharmaceuticals in both humans & animals and for crop protection. Despite avermectins are having complex chemical structures, but they are produced via synthesis in large scales for commercial use. Plant parasitic nematodes (PPNs) cause severe damages in all parts of their host plants, in addition to yield losses. The available strategies to control PPN include use of insecticides/nematicides but these have proved detrimental to environment and human health. Therefore, this scenario gave an opportunity for the utilization of avermectins (abamectin and emamectin) to control plant parasitic nematodes because of their chemical and biological properties, as well as relative safety. Avermectins have short half-lives and their residues can be eliminated easily through different food processing methods. Both abamectin and emamectin were very effective nematicides which proved capability of reducing PPNs significantly in various crops.
Analysis of factors influencing participation of farm households in watermelon production in some selected local government areas of Sokoto State, Nigeria
Published on: 28th February, 2020
OCLC Number/Unique Identifier: 8930822971
The study analyzed the factors influencing participation of farm households’ in watermelon production in the study areas. Three local government areas out of Sokoto state were purposively selected. Questionnaire was used to collect data. Multistage of sampling techniques were used to arrive at the sample size of 181 farm households’ for the study. Likert scale is used to analyze the level of participation of farm households’, frequency and inferential statistics were used to analyze the data. The findings revealed that (55.8%) of the farm households are within the ages of 25-30 years, majority (96.7%) are male It shows that majority (64.0%) of the farm households participated in watermelon production as a result of higher income generated. Multiple regression analysis result revealed significant relationships between farm household’s participation in watermelon production and their socio-economic characteristics at p < 0.05. The constraints faced by the farm households are storage technology and improved agricultural inputs. Most (63.5%) of the farm households believed that provision of subsidized agricultural inputs and market accessibility are forms of assistance that will encourages farm households to partake in watermelon production. It is recommended that government and donor agencies should encourage farm households’ by providing them with the modern agricultural inputs so as to influence them to participate fully into watermelon production irrespective of their Socio-economic differences.
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