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Suicide has become a major cause of human death during the last few decades. It is important to understand the dynamics of suicide and identify effective prevention strategies. In this work, bifurcation analysis and multi objective nonlinear model predictive control are performed on a suicide dynamics model. Bifurcation analysis is a powerful mathematical tool used to deal with the nonlinear dynamics of any process. Several factors must be considered, and multiple objectives must be met simultaneously. The MATLAB program MATCONT was used to perform the bifurcation analysis. The MNLMPC calculations were performed using the optimization language PYOMO in conjunction with the state-of-the-art global optimization solvers IPOPT and  BARON. The bifurcation analysis revealed the existence of limit and branch points. The MNLMC converged on the Utopia solution (best possible). The limit and branch points (which cause multiple steady-state solutions from a singular point) are very beneficial because they enable the Multi objective nonlinear model predictive control calculations to converge to the Utopia point (the best possible solution) in the model. It is proved (with computational validation) that the branch points were caused because of the existence of two distinct separable functions in one of the equations in the dynamic model. A theorem was developed to demonstrate this fact for any dynamic model.

Pushing forward with leveraging water resources, promoting international cooperation, and ensuring transparency in deep-sea mining operations. There is also a concern about where to discharge the toxins of unpurified water. Artificial Intelligence has created a dominance in the applications field with a totally automated system.Out of a thorough analysis completed with indicators, satellite radar, and A Journals, there are 30 years of research and 8 years of monitored testing to achieve accuracy and relevance. The patents in place are, Oceanic Mining System (4446636), Flexible Solar Skin in Combination with an Airplane (4768738), Cargo Torpedo (4421050), Oceanic seaplow system (4398362), and previous articles like “Is Extracting Lithium and deep-sea mining more sustainable?”, “AI as a Means of Water Purification Protection”, “Global Water Distribution”, and “Can Deep Sea Water be Processed into Potable Water and Distributed into the Middle East’?To report some ballpark numbers on the proposal and how we would navigate these projects, there will be an exact location of where the plant will be built as well as a water/salinity report of the water being treated. There are still issues with analyzing the cost of desalination compared to other alternatives. Deep Sea Water proves to be a higher quality water and the investment is well worth it. The surveys lean toward clients preferring the International Standards Operating Procedure. All recipients agree there should be a sense of urgency on water shortages. Currently, AI has proven to be a vital asset in eliminating biases and expenses.

A field study was carried out to evaluate the efficacy of pendimethalin 500 EC (trade name: Pendimight®) and oxyfluorfen 240 EC (trade name: Harris®) to control weeds in direct-seeded onion (Allium cepa L.). Pendimethalin and oxyfluorfen were applied solely at reduced rates (1.35 and 0.17 kg a.i. ha-1), and at the recommended rates (1.8 and 0.25 kg a.i. ha-1) as pre-and post-emergence herbicides, respectively. Both herbicides were also applied sequentially at the same doses. Ten weeks after sowing (WAS), the application of pendimethalin alone provided better weed control (62% - 65%) than oxyfluorfen alone (33% - 43%) when they were applied at the lower and recommended rates, respectively. Sequential applications of the two herbicides as pre-and post-emergence herbicides, outperformed applications of the two herbicides alone, and resulted in the best weed control (79% to 85%), lowest weed dry weight (18.35 to 35.60 g.m-2), significantly increased plant height and the number of leaves per plant, and resulted in a ten-fold higher onion yield (24.64 to 26.37 t. ha-1) compared with the Un-weeded control (2.27 t. ha-1). There were no significant differences observed between the treatments on the emergence (%) of onion seeds and the survival of onion seedlings. Sequential applications of pendimethalin and oxyfluorfen is a promising techniques for weed control in direct-seeded onions in Sudan.

Introduction: Extracellular Traps (ETs) are fibers composed of chromatin and cytoplasmic proteins, which can trap and kill pathogens by the phenomenon called ETosis. They are released by neutrophils, macrophages, and monocytes, and can be found in semen. The aim of this presentation is to evidence of the indirect effect of SARS-CoV-2 in semen by ETs.Patients and methods: Experimental design: retrospective descriptive observational study.Semen samples from two groups were studied following WHO guidelines: 1) SARS-CoV-2 infected donors (n: 5; at 7, 15, 30, 60, and 90 days after PCR diagnosis); 2) COVID-19 positive patients assisted in our laboratory between 2021 and 2022 (n: 70). They were observed in fresh and in Papanicolaou-stained smears by CASA and light microscopy; the presence of macrophages, spermiophages, ETs and hyperviscosity were recorded while neutrophilic concentration was calculated. Two control groups were designed: a) Patients belonging to group 2, studied before de pandemia (n: 13); b) Culture-negative semen samples (n: 28).Results: In the first group, ETs were observed in all the samples, while only 18% had leucospermia. Macrophages, spermiophages, and hyperviscosity were recorded in 68%, 27%, and 36% of the studied cases respectively.In the second group, ETs were present 100% in the acute phase (< 90 days after diagnosis) and decreased to 71% in the later stage (90 to 270 days). The trapped sperm were non-progressive motile or immotile alive or dead.No traps were found in either control group.Conclusion: In our study ETs were the most sensitive seminal marker of SARS-CoV-2 infection.

Background: The motivation of this paper is to analyze the growing air pollution level in the city of Bengaluru, as it was once a green city but is now facing problems with the use of private vehicles, such as increasing levels of air pollutants. Green buildings focus on reducing their negative environmental impacts by using less energy and water, and causing less disruption to the environment during construction. Green buildings, which also strive to enhance human health through the design of healthy indoor spaces, are arguably less well-known.Objective: The main objective is to analyze the most suitable zone in Bangalore for the construction of green buildings. The review of existing green building technologies with the use of natural materials, renewable energy, water conservation, and indoor air quality.Method: The methodology will include a study of six green building literature reviews with eminent researchers and scientists. The main principles of green building include having indoor air quality of Nitrogen oxides, volatile organic compounds, and particulate matter are the most common air impurities released into the atmosphere by the variability of natural processes and human actions. The advantages of lessened energy and water use are well known, but the potential advantages of green buildings for human health have only lately come into focus. In addition, case study review for Electronic City, Whitefield, and International Airport in BangaloreResult: To address the comparative study of case study review, Bangalore city data was collected regarding the pollutant levels, then linear regression models were created and reviewed to design green buildings in the future. Conclusion: The goal of the study is to comprehend how toxins, a rise in urban population density, the usage of novel artificial resources, and traffic contamination all work together to worsen indoor air quality and increase harmful impacts on people.

Agrobacterium rhizogenes ATCC 15834 wild type strain was transformed with the binary vector pBI121 using the heat shock method. The transformed Agrobacterium was then tested for virulence through tobacco leaf explant transformation. Compared to the non-transformed Agrobacterium, the transformed Agrobacterium showed reduced virulence, producing significantly lower number of hairy roots in tobacco leaf explants. Although the transformed Agrobacterium showed reduced virulence, it was able to transfer the T-DNA of the binary vector into the plant genome, resulting in stable GUS expression in the generated hairy roots. This indicated that in addition to the transfer DNA (T-DNA) from its root inducing (Ri) plasmid, the transformed Agrobacterium is also capable of transferring the binary vector T-DNA and allowing the integration of a foreign gene. Results also showed that hairy root generation efficiency of the transformed Agrobacterium varied with the concentration of the selection agent (kanamycin). Hairy root generation efficiency (hairy roots·explant-1) progressively increased with decreasing concentrations of kanamycin; and the efficiency was highest in the absence of kanamycin. Generated hairy roots showed very strong to tiny GUS expression even those that grew under the highest concentration of the kanamycin (50 mg·L-1). This indicated that co-transformation and efficient transgene expression does not always occur.

Psidium guajava (guava) is an important crop and economic resource in many tropical countries and Brazil stands out as one of its major commercial producers. The guava crop has been severely attacked by the plant parasitic nematode Meloidogyne enterolobii which has caused drastic reduction of productivity and, in some cases, even total loss of cultivated areas. The use of resistant rootstocks that are tolerant to these soil pathogens can be a low-cost solution to this pathogen, which has established itself as one of the major constraints for the cultivation of guava in Northeast Brazil. The objective of this work was to evaluate the reaction of P. guajava and P. guineense to M. enterolobii infection under greenhouse conditions, with an infection period of 60 days. 12 P. guineense, and 4 P. guajava were evaluated. The host response to the nematode infection was evaluated according to the following parameters: gill index (GI), reproductive factor (RF), and reduction of reproductive factor (RRF). Considering the RRF criteria, the P. guineense genotypes, AR1, AR3, AR4 and AR10 were considered resistant. The RF index was considered inadequate to evaluate resistance in the 60 days period, due the slow development of the parasite in P.guineense.

In recent years, studies on the utility of essential oils and their components in the preservation of food commodities in order to enhance shelf-life has been successfully carried out. These essential oils and their components (Carvacrol, Eugenol and Cinnamaldehyde) can be used as antimicrobials and food preservative agents; however, their use raises concerns because of several reported side effects of synthetic oils. Due to their antimicrobial potential, essential oil constituents could be used as food preservatives for grains, cereals, vegetables and fruits. The aim of the treatments was carried out on the treated cotton packaging to maximize the benefit from its antimicrobial activity to extend grain Storage periods. The cotton fabrics treated in three steps: Carboxymethylation of cotton fabric (CMC) Cationization of cotton fabric 3-Treatment of the fabrics by reactive-cyclodextrine (RCD). Modified and unmodified cotton fabrics were treated with antibacterial agent by dipping them at room temperature for 2 hours under stirring in dimethyl sulfoxide (DMSO) solution containing 200, 250, 250 ppm of Eugenol, carvacrol and cinnamaldehyde respectively the samples were then roll-squeezed at pick up 100% and dried at room temperature. All treated and untreated fabrics were subjected to antimicrobial tests. Cotton fabric composites treated with cinnamaldehyde had the highest impact on reducing microbial preparation during storage period followed by cotton fabric composite treated by Carvacrol followed by cotton fabric composite treated by Eugenol which is less impactful to reduce microbial count during the storage period.

Ubiquitination is a kind of posttranslational modification of proteins in eukaryotes, and it plays an important role in the growth and development of organisms. The ubiquitination of proteins is a cascade enzymatic reaction involving three enzymes. The homologous to E6-AP carboxy terminus ubiquitin-protein ligases (HECT E3s) family is an important ubiquitin-protein ligases family. The family all have a HECT domain of approximately 350 amino acids in the C-terminus. However, studies on plant HECT E3s, such as structural features, prediction of HECT domain function, and their regulatory mechanisms, are very limited. In this paper, Arabidopsis thaliana HECT family genes were analyzed, including gene structure and functional domains and its limited known functions in protein degradation, gene transcription regulation, epigenetically regulation or other functions, finally speculate their roles in plant morphologies, aging or responsive to environmental stress.

Introduction: Necrotizing Fasciitis (NF) is a rapidly progressing and life-threatening soft tissue infection, exceedingly rare but often fatal in neonates. This case series highlights the rarity, fulminant nature, and poor prognosis of neonatal NF by presenting four cases.Case presentation: Four neonates, aged 12-16 days, presented with rapidly spreading, tender, erythematous, and indurated skin lesions on their backs, initially resembling burns. Systemic symptoms like fever, lethargy, and poor feeding were common. Despite empirical antibiotics, the lesions progressed to necrosis, often with bullae formation. Microbiological cultures revealed polymicrobial growth in three cases (E. coli, Pseudomonas sp., Klebsiella, and MRSA) and monomicrobial growth of MRSA in one case, frequently exhibiting antibiotic resistance. Surgical debridement was performed in three cases. Despite aggressive management, two neonates succumbed to sepsis and multi-organ dysfunction. The other two neonates recovered after prolonged antibiotic therapy and wound care.Discussion: These cases underscore the diagnostic challenges and rapid progression of NF in neonates. The consistent presentation after 10 days of birth, rapid lesion spread mimicking burns, and predilection for the back were notable features. Polymicrobial infection was frequent. Early recognition, aggressive broad-spectrum antibiotics, and timely surgical debridement are crucial for improving the poor prognosis associated with this condition.