This article provides a comprehensive overview of the properties, applications, and fabrication techniques of nanofibers, which are characterized by their ultrafine diameters and unique features such as high surface area and aspect ratio. These attributes render nanofibers particularly advantageous for a wide range of applications, especially in the biomedical sector, encompassing areas like tissue engineering, drug delivery, and wound dressing. The article highlights various studies that illustrate the potential of nanofibers in addressing healthcare challenges, particularly their utilization in scaffolds for regenerative medicine and as carriers for controlled drug delivery. Furthermore, it discusses different preparation methods for nanofibers, including electrospinning and alternative techniques, while stressing the importance of polymer selection in achieving optimal drug-release properties. The article also delves into the application of nanofibers in tissue engineering, specifically for bone, cartilage, and vascular applications, and examines their emerging roles in organ-on-a-chip technology and contraceptive development. In conclusion, the article emphasizes the versatility and significance of nanofibers in advancing medical technologies and their potential to address contemporary health challenges. Collaborative efforts between material scientists and biologists are essential to foster interdisciplinary research aimed at improving electrospinning methodologies.
The escalating volume of solid waste due to rapid urbanization, population growth, and industrialization poses significant environmental and public health challenges. Improper disposal of solid waste, especially organic and municipal garbage, leads to pollution of soil, air, and water, causing a surge in health risks and ecosystem degradation. Traditional waste management practices are often inefficient, expensive, and time-consuming. Composting and vermicomposting have emerged as eco-friendly, cost-effective, and sustainable alternatives for organic waste management. Vermicomposting, which employs earthworms to decompose organic waste into nutrient-rich compost, has shown potential in improving soil fertility, reducing pathogenic microbes, and recycling essential nutrients like nitrogen, phosphorus, and potassium. Various organic wastes such as agricultural residues, municipal waste, animal dung, and market garbage have been effectively treated through vermicomposting using species like Eisenia fetida and Eudrilus eugeniae. This review emphasizes the technological, environmental, and agricultural benefits of vermicomposting in transforming biodegradable solid waste into valuable compost, promoting sustainable waste management practices, and enhancing agricultural productivity.
The present study was aimed to screen and quantify the phytochemicals by qualitative and quantitative analysis in methanol and aqueous leaf and stem extracts of Marsilea quadrifolia(L.). In qualitative analysis, the phytochemical compounds such as tannins, saponins, flavonoids, steroids, terpenoids, triterpenoids, alkaloids, carbohydrates, proteins, anthroquinones, phenolic compounds and phytosterol were screened. Among these phytocompounds tannins, saponins, flavonoids, steroids, alkaloids, carbohydrates, proteins and phenolic compounds were observed in methanol and aqueous leaf and stem extracts of M. quadrifolia. Anthroquinones were absent in both leaf and stem extracts of M. quadrifolia. The content of phenolic compounds 8.34±0.92 mg/g and 7.31±0.46 mg/g, flavonoids 7.46±0.64 mg/g and 6.45±0.68 mg/g, alkaloids 6.12±0.51 mg/g and 5.89±0.61 mg/g, tannins 6.58±0.72 mg/g and 6.07±0.56 mg/g and saponins 5.32±0.48 mg/g and 6.30±0.58 mg/g were determined in leaf and stem of M. quadrifolia, respectively. So, the present study confirmed that the presence of phytocompounds in leaf and stem of M. quadrifolia.
As time goes on, more and more people are using drugs in dangerous ways. This rising percentage of people abusing drugs is leading to an increase in violent behaviors connected to them. The present article will summarize and present cases of mass violence caused by drugs, displaying the harm they may cause if not regulated properly. A literature search of JSTOR, AJPH, IJERPH, Journal of Addictive Reviews, Journal of Addiction Research and Therapy, Google Scholar, CDC, CNN, New York Times, Detroit News, and ABC News was conducted from February 16, 2023, to November 03, 2024. In 2016, 56.2 million people died worldwide. There are an estimated 10,000 people who are killed each year in the United States as a direct result of drugs. Worldwide, 70 million people were diagnosed with a drug use disorder. In the global general population, 0.3%-0.6% of people are diagnosed with this disorder. 10%-69% of people in prison are diagnosed as well. From 1995 to 2000, 41% of violent crimes committed against college students and 38% of violent crimes committed against non-students were committed by an offender thought to be on drugs. Drugs have a clear connection to mass violence, and further regulation is needed for the benefit of public health and safety.
Vegetable production by grafting is a technique which it has made possible to resume agricultural soils which previously could not be produced due to stress generated by various abiotic factors, like a lack of water, stress by high or low temperatures, and or heavy metal contamination, among them. It has been documented and defined a number of graftings which they are tolerant to different factors; however, when it comes to auscultating information related to understand the molecular responses and observe what are the biochemical changes and physiological responses of grafted plants, it is dispersed. The current paper attempts to provide basic information documented on technique, addressing the molecular, biochemical and physiological responses, and thus get a clear perspective on the use of grafts, making this practice be used with most frequently by all its advantages.
Dental implantology represents a cornerstone of modern restorative dentistry, providing long-term functional and esthetic rehabilitation of missing teeth. The process of osseointegration—first introduced by Brånemark—refers to the direct structural and functional connection between living bone and the surface of a load-bearing implant [Brånemark, 1985].
Diseases are a major cause of post-harvest losses depending on season, region and management practices. Chemical control is the most used but with serious consequences for human health and the environment. This forces us to carry out more exhaustive studies on botanical products. The general objective of the present study was to evaluate the effect of citrus extracts for the control of pathogens that cause post-harvest diseases in tomato fruit. The product to be evaluated is of botanical origin from citrus extracts. Doses were evaluated (0, 666, 1000, 2000, 4000, 8000 ppm). The treatments were located at a temperature of 25°C±2 and 45% relative humidity (rH). The design used corresponded to a completely random design. The least significant difference was estimated by Tukey Multiple Range test at P=0.05. The statistical tests were performed through the SAS computer program. The results indicate that the pathogens detected and identified correspond to Alternaria tenuissima; Botrytis cinerea; Cladosporium fulvum; Colletotrichum coccodes; Fusarium oxysporum; Geotrichum candidum; Rhizopus stolonifer and Stemphylium macrosporoideum. Our conclusion is that the efficient doses correspond to 666, 2000 and 8000 ppm. With the application of citrus extracts, the damage percentage of tomato fruit was reduced in relation to the control treatments. Based on the results with the application of citrus extracts, the shelf life of the tomato was lengthened.
The armored scale Aulacaspis alisiana, is a serious invasive pest of the Japanese silver tree, Neolitsea sericea, causing serious damage to the tree in Japan. However there are currently no control approaches available for it, complicated by shortage of information on the pest. We studied life history strategies of A. alisiana on N. sericea in Fukuoka Prefecture with a view to providing a basis for formulating sustainable control based on an understanding of the behavior of the pest and potential role of its natural enemies. We established that A. alisiana had three overlapped generations in Fukuoka, with generation times ranging between 65 and 71 days. The adults were relatively fecund, with each female producing between 60 and 67 eggs, with high hatchability, >78%. The pest settled on the lower side of leaves, and although it generally preferred younger leaves, it did not attack newly emerged leaves. Natural enemy groups comprising ants, spiders and beetles (coccinelids) played an important role in regulation of the pest population, with natural mortality of about 30%. They could thus form a critical component of an integrated management approach for the pest in Fukuoka.
Cai Zi, Sun Menghan*, Zhang Chunhui, He luyao and Yang Zailin
Published on: 3rd September, 2025
This study proposes a new type of flange-widened bone-type semi-rigid frame node, and takes a 4-story frame as an example, uses the finite element software Abaqus to analyze its seismic performance under different seismic waves, and compares it with the traditional rigid connection frame. The results show that the stiffness of the new node frame is slightly lower than that of the tradition rigid node frame, which reduces the horizontal displacement of each layer under the action of earthquake, optimizes the deformation capacity, and enhances the force performance and ductility, the maximun value of the base shear force is lower than that of the traditional rigid frame, which can effectively disperse and dissipate the seismic energy andimprove the overall stabitity of the structure; the elastic-plastic interlayer displacement angle is less than 1/50 under rare earthquakes, which meets the requirements of the specification and can achieve the goal of “no collapse in a large earthquake”. In addition, the node can effectively improve the safety and reliability of the structure in actual engineering.
Isabella Allana Ferreira*, Júlia dos Santos Fonseca, Ítalo Stoupa Vieira, Lorendane Millena de Carvalho and Jackson Victor de Araújo
Published on: 9th September, 2025
The resistance to anthelmintics in poultry farming and the challenges with the restricted use of drugs in organic farms make the use of biological controllers an innovative bridge to verminosis control. This paper aims to evaluate the efficacy of the larvicidal fungus Duddingtonia flagrans and the ovicidal fungus Pochonia chlamydosporia in Hy-line Brown (Gallus Gallus Domesticus) layer farms. Both fungi were combined in the core of the feed administered to the birds of the treated groups. 28,000 birds were used and divided into three treated groups (TG) in which the feed containing the fungus was administered. The poultry house itself manufactures the birds’ feed; the formula was included in the nucleus at a dose of 100 grams per ton of feed for 7 months. The concentration was 105 chlamydospores of P. chlamydosporia and D. flagrans per gram of the formulation. The control group (CG) received regular food from the farm. The birds were separated into four sheds with 7,000 birds in each. The egg per gram of feces (EPG) testing was performed using fresh fecal samples collected from the sheds over six months. Weather data was collected during the experiment. There was a reduction in the EPG count into three treated groups. The most prevalent helminth was the genus Ascaris. The formulation tested shows little efficacy in this dosage. Key points:• The use of the fungus P. chlamydosporia and D. flagrans in organic farms;• Use of biocontrol agents without chemicals in poultry;
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